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E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
AKI is a well known risk factor for development of CKD. Approximately 1/3rd of AKI patients would progress to CKD. The bidirectional nature of AKI and CKD is well known. CKD is a risk factor for occurrence of AKI and AKI progresses to CKD. Common factors identified for progression to CKD were increasing age, diabetes, recurrent AKI, severe AKI and episodes of AKI. We could not assess the episodes of AKI during follow up period.
Inclusion criteria :
All those patients with severe AKI as per KIDIGO stage 3 were included in the study
Exclusion criteria :
Patients with pre existing Chronic kidney disease were excluded
Patients admitted with severe AKI were supported with regular intensive care and the Kidney replacement therapies.Indications for KRT were as per the literature.Modalities of KRT were hemodialysis , peritoneal dialysis.Indication for KRT option was based on hemodynamic stability .Bicarbonate based hemodialysis was given with standard 4008 Fresenius machines using dialysers with surface area of 1.3m2 surface area.All severe AKI patients were assessed for development of acute kidney disease (AKD) and chronic Kidney disease. Presence of AKD and CKD was based on KDIGO definitions.
The data was collected based on case records of patients admitted between 2018-2022.Demographic data, laboratory data, status at discharge , in hospital mortality were collected .An assessment for the development of CKD was done in all the survivors at the end of 7 year period.Follow up period ranged between 3years-7 years. Mean follow up period was 5 years and the median follow up was 18 months
We analysed case records of 815 patients with severe AKI (KDIGO STAGE AKI 3 ) ,of whom 300 patients died at the end of one week. Remaining 515 patients were followed up over the next 3years -7 years period. Mean age of our group was 46+16 years. Men were slightly higher in number compared to women. Prevalence of comorbidities such as diabetes and hypertension were between 16-26%.Most common cause of AKI in our cohort was sepsis followed by cardiac causes and Tropical AKI .Both cardiac causes and tropical AKI accounted for 40% and sepsis accounted for 42% of causes of severe AKI.
On analysis of factors influencing the progression of AKI to AKD, none of the factors including the cause, underlying comorbidity or severity of renal insufficiency were found to be significant except the old age. On multi variate analysis , only increasing age was associated with progression to AKD.Progression to CKD :
All 515 patients were followed up for a period of 3years -7 years.CKD was diagnosed based on KDIGO definitions. All 515 patients were checked for hypertension, proteinuria , GFR calculation based on serum creatinine. Of this 515, 48 patients died during the course of follow-up and remaining 467 patients were classified to have CKD as per GFR calculation. Proteinuria was observed in 82 patients and hypertension in 74 patients .About 148 patients satisfied the definition of CKD , of whom 11% (57 /148 ) patients were in CKD stage 3b and 6.7%(35 /148 ) patients reached ESRD. About 319 patients (68.3%) had normal renal functions at the end of follow-up period
On analysis of factors influencing progression to CKD , it was observed that women had higher tendency to progress to CKD than men (p value was not found significant), age , diabetes, hypertension, severity of renal insufficiency degree of proteinuria were not associated with progression to CKD. On multivariate analysis, underlying cardiovascular disease was found to have statistically significant association with progression to CKD
Long term follow up of AKI is mandatory .28% of our cohort progressed to CKD.Presence of underlying cardiovascular disease was found to have statistically significant associated with progression to CKD.
