CAUSES BEHIND DELAY IN PERMANENT ANGIOACCESS CREATION AT INITIATION OF HEMODIALYSIS: A SINGLE CENTRE STUDY

 

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https://storage.unitedwebnetwork.com/files/1099/405ba7b323589b45bcd6148b8fbf3f8e.pdf
CAUSES BEHIND DELAY IN PERMANENT ANGIOACCESS CREATION AT INITIATION OF HEMODIALYSIS: A SINGLE CENTRE STUDY

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Tajammul
Waqar
Tajammul Waqar tajammulwaqar@yahoo.com Sindh Institute of Urology and Transplantation Nephrology Karachi Pakistan *
Sajid Islam Bhatti sajidibhatti@yahoo.com Sindh Institute of Urology and Transplantation Nephrology Karachi Pakistan -
Sidra German dr.sidragerman@gmail.com Sindh Institute of Urology and Transplantation Nephrology Karachi Pakistan -
Imran Mangi info@siut.org Sindh Institute of Urology and Transplantation Nephrology Karachi Pakistan -
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Despite clinical guidelines recommending arteriovenous fistula (AVF) as the optimal vascular access for hemodialysis, over 60% of Pakistani patients initiate dialysis via temporary catheters. This study investigates the patient-centered factors contributing to delayed AVF creation.

A cross-sectional study of 121 patients initiating hemodialysis via temporary access at a tertiary care center. Data collection included demographic characteristics, clinical parameters, and a 12-item questionnaire assessing beliefs about AVF creation. Multivariate regression analysis identified predictors of delayed AVF creation.

The cohort (mean age 45.2±14.8 years, 72.7% male) had strong theoretical agreement with early AVF creation (94.2%), yet experienced substantial delays (median: 17 months; mean: 36.8 months). Multivariate analysis revealed lower education level as the strongest predictor (graduate education: -43.9 months, p=0.005), followed by belief in alternative therapies (+35.6 months, p<0.001), perception of AVF as hopelessness (+16.9 months, p=0.018), and older age (+0.48 months/year, p=0.014). Symptomatic kidney stone disease predicted shorter delays (-32.4 months, p=0.013). Referral time showed weak correlation with AVF delay (r=0.26, p=0.004).

AVF creation delays are primarily driven by socioeconomic and psychological factors rather than clinical necessity. Targeted interventions addressing health literacy, misconceptions about alternative therapies, and psychological barriers are essential for improving vascular access outcomes.

Kewords