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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Cognitive dysfunction (CODY) is increasingly recognized as a significant complication among patients undergoing maintenance hemodialysis (MHD). This study aims to identify the factors affecting cognitive function in the hemodialysis population.
This cross-sectional study was conducted at the Sindh Institute of Urology and Transplantation (SIUT) in Karachi, enrolling 224 adult patients who had been on hemodialysis for at least six months. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) prior to dialysis sessions, and the outcomes were categorized based on MMSE scores. Demographic data, comorbidities, duration of hemodialysis, and laboratory parameters such as hemoglobin, serum urea, and creatinine levels were also evaluated. Statistical analysis included both univariate and multivariate approaches to identify independent risk factors for cognitive impairment.
Cognitive impairment was observed in 31.3% of the patients, with 87.1% exhibiting mild cognitive impairment and 12.9% severe impairment. Advanced age, the presence of diabetes, longer duration on hemodialysis, elevated serum urea levels, and lower hemoglobin levels were significantly associated with cognitive dysfunction. On multivariate analysis, diabetes (OR=13.56), duration of hemodialysis ≥2 years (OR=0.44), elevated serum urea (OR=0.988), and decreased hemoglobin levels (OR=1.562) were identified as independent predictors of cognitive impairment.
The study underscores the high prevalence of cognitive dysfunction in the hemodialysis population and identifies diabetes, prolonged hemodialysis duration, elevated serum urea, and anemia as significant risk factors. Regular cognitive screening and targeted management of these risk factors could improve the quality of life and reduce morbidity in this vulnerable population. Further research is recommended to explore the mechanisms of cognitive decline in MHD patients and to develop effective interventions.
