QUALITY OF LIFE IN KIDNEY TRANSPLANTATION RECIPIENTS: A SINGLE-CENTRE EXPERIENCE FROM A LOWER-MIDDLE INCOME COUNTRY

 

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https://storage.unitedwebnetwork.com/files/1099/8252253563d75634b601df8a8ac2e1b0.pdf
QUALITY OF LIFE IN KIDNEY TRANSPLANTATION RECIPIENTS: A SINGLE-CENTRE EXPERIENCE FROM A LOWER-MIDDLE INCOME COUNTRY

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Nazar Ul Hassan
Jafry
Nazar Ul Hassan Jafry drjafry12@gmail.com Sindh Institute of Urology and Transplantation Nephrology Karachi Pakistan *
Anum Rizwan secretariat@siut.org Sindh Institute of Urology and Transplantation Nephrology Karachi Pakistan -
Tajammul Waqar tajammulwaqar@yahoo.com Sindh Institute of Urology and Transplantation Nephrology Karachi Pakistan -
Sajid Islam Bhatti sajidibhatti@yahoo.com Sindh Institute of Urology and Transplantation Nephrology Karachi Pakistan -
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Chronic Kidney Disease (CKD) is a growing global health concern, with kidney transplantation (KT) recognized as the optimal kidney replacement therapy (KRT) for improving health-related quality of life (HRQoL) in these patients. However, data on HRQoL post-KT in lower-middle-income countries (LMICs) like Pakistan remain limited.

This study assessed HRQoL in KT recipients at the Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan, to evaluate the impact of transplantation on physical, mental, emotional, and social well-being of KT recipients (KTRs).

A cross-sectional study was conducted among 205 adult KTRs (≥1 year post-transplant) using the SF-36 questionnaire. Sociodemographic data, physical symptoms, psychological status, and social functioning were analyzed. Statistical analysis was performed using SPSS v. 22, with p < 0.05 considered significant.

The mean age of all KTRs was 38.1 ± 10.6 years, with 78% males. The mean post tansplant duration was 8.9 ±  6.1 years (Range: 1-34 years). The mean SF-36 score was 99.5 ± 4.81, indicating high HRQoL. Physical function (96.8 ± 8.5) and social functioning (95.5 ± 15.7) scores were notably high, while general health perception was lower (82.5 ± 22.5). Males reported significantly better physical function than females (p = 0.031). No significant associations were found between HRQoL and marital status, education, income, or time since transplantation (p > 0.05).

KT significantly improves HRQoL, particularly in physical and social domains, among Pakistani recipients. Gender disparities highlight the need for tailored post-transplant care for females, while the minimal impact of sociodemographic factors suggests the effectiveness of structured transplant programs in LMICs. These findings support expanding KT access while emphasizing gender-sensitive rehabilitation strategies.

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