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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Inconsistency exists about whether dietary sodium intake is associated with increased risk of chronic kidney disease (CKD) progression. Drawbacks regarding ways to measure sodium intake and to handle time-dependent confounding from proteinuria may be attributed to the inconsistency. Here, we prospectively investigated kidney failure events in relation to baseline or time-updated 24-hour urinary sodium excretion (UNaV) among patients with CKD stage 3 and 4.
Study participants came from a prospective CKD cohort recruited in out-patients at a single tertiary hospital. UNaV was split into tertiles (<120, 120- <180.5, and ≥180.5 mmol/24h) or according to whether ≥120 mmol/24h. Outcomes included incidence of kidney failure with replacement therapy, estimated glomerular filtration rate (eGFR) declining for ≥50 % or composite of the two. Cox regression model was used to estimate the association between baseline UNaV and outcomes, while marginal structural model to assess the effect of time-updated UNaV and address time-dependent confounding of proteinuria (Figure 1).
Totally, 307 patients were included, with mean age of 55±15 years, 51.14% of male and average UNaV of 157.30±68.60 mmol/24h. During a median follow-up of 3.31 years, 15 events of kidney failure with replacement therapy, 58 eGFR halving and 61 composite events occurred. Baseline UNaV was not associated with study outcomes after adjusting for 24-hour urinary protein, while maintaining UNaV in ≥180.5 mmol/24h throughout follow-up was associated with a significantly higher risk of eGFR halving or composite events with hazard ratios of 6.29 (95% confidence interval: 1.47, 26.86) and 6.12 (1.46, 25.74), respectively, comparing to <120 mmol/24h.
High dietary sodium intake is associated with increased risk of CKD progression among patients with CKD stage 3 and 4.
