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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
While deceased donor kidney transplantation is steadily expanding worldwide, living donor kidney transplantation continues to predominate in many regions, including India. Spousal donor transplantation, an HLA-unrelated yet socially anchored form of living donation, has emerged as a key contributor to donor expansion and reflects changing societal dynamics. This study assessed the clinical and sociodemographic outcomes of spousal versus biologically related living donor kidney transplants performed in a state-run tertiary care centre in Tamil Nadu, India.
A retrospective analysis included all living donor kidney transplants performed between January 2017 and December 2019. A total of 115 recipients were studied: 92 with biologically related donors and 23 with spousal donors. Demographics, hemodialysis (HD) vintage, immunosuppressive therapy, graft function, rejection, infection, graft loss, and mortality were analyzed. Median follow-up was 58 months (IQR 34–69). Statistical analysis was performed using standard tests, with p < 0.05 considered significant.
Spousal recipients were older (40.5 ± 3.2 years) than related recipients (28.4 ± 1.4 years; p < 0.0001), while spousal donors were younger (36.1 ± 3.0 vs 49.1 ± 1.5 years; p < 0.0001). Hemodialysis vintage was comparable (8.8 vs 7.0 months; p = 0.18). Basiliximab induction was used in 91.3% (n = 21) of spousal and 45.7% (n = 42) of related transplants (p < 0.0001). Immediate graft function was achieved in 52.2% (n = 12) of spousal and 43.5% (n = 40) of related recipients (p = 0.51). Acute rejection occurred in 34.8% (n = 8) of spousal and 27.2% (n = 25) of related recipients (p = 0.47). Infection rates were 65.2% (n = 15) in spousal and 60.9% (n = 56) in related recipients (p = 0.34). Graft loss occurred in 17.4% (n = 4) and 14.1% (n = 13) respectively (p = 0.74). Mortality was 17.4% (n = 4) in spousal and 10.9% (n = 10) in related groups (p = 0.47).
Spousal donor renal transplantation demonstrated graft and patient outcomes comparable to biologically related living donor transplantation, confirming its safety and efficacy despite HLA disparity. Comparable rejection, infection, and survival rates suggest that optimized induction and maintenance immunosuppression can effectively overcome immunologic mismatch. The predominance of female donors and male recipients highlights the persistent gender imbalance in living donation and emphasizes the need for greater social awareness. Given the relatively younger age of spousal donors, vigilant long-term follow-up is warranted to ensure donor safety and renal health. Overall, spousal donation represents a viable strategy to bridge the living donor gap without compromising long-term outcomes.
