Regional difference in access to renal replacement therapy following peritoneal dialysis first policy in Thailand

 

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Regional difference in access to renal replacement therapy following peritoneal dialysis first policy in Thailand

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Hitomi
Kimura
Hitomi Kimura kimura-hitomi@hotmail.co.jp Japan Institute for Health Security Institute for Global Health Policy Research, Bureau of Global Health Cooperation Shinjuku Japan *
Hayato Yamana Hayato Jichi Medical University Data Science Center Shimotsuke Thailand -
Arinda Ma-a-lee Arinda Prince of Songkla University, Pattani campus Department of Mathematics and Computer Science, Faculty of Science and Technology Pattani Japan -
Eiko Saito Yuta Sustainable Society Design Center, Graduate School of Frontier Sciences the University of Tokyo Kashiwa Japan -
Yuta Taniguchi Taniguchi Japan Institute for Health Security Institute for Global Health Policy Research, Bureau of Global Health Cooperation Shinjuku Japan -
Mariko Hosozawa Hosozawa Japan Institute for Health Security Institute for Global Health Policy Research, Bureau of Global Health Cooperation Shinjuku Japan -
Hisateru Tachimori Tachimori Japan Institute for Health Security Institute for Global Health Policy Research, Bureau of Global Health Cooperation Shinjuku Japan -
Pathipak Namahoot Namahoot National Health Security Office Monitoring and Evaluation Cluster Nonthaburi Thailand -
Jutatip Thungthong Thungthong National Health Security Office Policy Advocacy Unit Nonthaburi Thailand -
Tanita Thaweethamcharoen Thaweethamcharoen National Health Security Office Monitoring and Evaluation Cluster Nonthaburi Thailand -
Tippawan Liabsuetrakul Liabsuetrakul Prince of Songkla University, Hat Yai campus Department of Epidemiology, Facongkhlaulty of Medicine Songkhla Thailand -
Virasakdi Chongsuvivatwong Chongsuvivatwong Prince of Songkla University, Hat Yai campus Department of Epidemiology, Faculty of Medicine Songkhla Thailand -
Hiroyasu Iso Iso Japan Institute for Health Security Institute for Global Health Policy Research, Bureau of Global Health Cooperation Shinjuku Japan -
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In 2008, Thailand implemented a policy known as "Peritoneal Dialysis (PD) First" under its Universal Coverage Scheme. This policy designated PD as the initial modality of renal replacement therapy (RRT) for eligible patients with end-stage kidney disease. Although the policy was designed to improve accessibility to RRT, little is known about how it has influenced geographical equity in access to RRT services. This study investigated nationwide changes between 2015 and 2019 in the distribution of institutions offering PD, hemodialysis (HD), and kidney transplantation (KT), as well as regional patterns in patients receiving these treatments. We also examined whether disparities are associated with socioeconomic development levels. 

We utilized the national RRT registration database, managed by the National Health Security Office, which covers approximately 76% of the Thai population. The number of healthcare institutions offering PD, HD, and KT was evaluated annually at national and provincial levels. For each province, we calculated the age- and sex-standardized ratios of PD and HD utilization using the 2015 national population of the Universal Coverage Scheme as a reference. The extent of regional variation was assessed by calculating the standard deviation of these ratios each year. We also examined associations between RRT utilization and provincial Human Achievement Index scores, which reflect various aspects of socioeconomic development, using one-way analysis of variance.

A total of 57,273 patients initiated RRT from 2015 to 2019. Of these patients, 38,522 received PD, 17,947 received HD, and 804 underwent KT. The number of institutions providing PD increased from 168 to 259, while those offering HD increased from 486 to 594. The proportion of PD among new RRT cases increased from 63.5% to 69.9%, while HD decreased from 34.4% to 29.2%, and KT declined from 2.1% to 0.9%. The standard deviation of the provincial standardized PD ratios increased from 0.46 in 2015 to 0.87 in 2019, indicating a widening regional gap in utilization. The HD ratios remained relatively stable, with standard deviations ranging from 0.60 to 0.64. Although many provinces showed an increase in PD utilization, Bangkok experienced a notable decrease. The HD utilization showed consistent positive associations with the Human Achievement Index throughout the study period, suggesting that more developed provinces used HD more frequently. In contrast, association between PD utilization and the index were observed only in 2015 and were not statistically significant in subsequent years.

The PD First policy in Thailand contributed to a substantial national increase in both access to PD and the number of institutions delivering RRT services. However, the regional disparity in PD utilization became more pronounced during the study period. Additional efforts may be needed to address these emerging inequalities. Findings from Thailand’s experience may serve as guidance for other countries that aim to scale up cost-effective RRT services.

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