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E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
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Kidney disease, particularly chronic kidney disease (CKD) disproportionately affects women and is accompanied by sex-specific complications (e.g., menstrual disorders, earlier menopause, pregnancy complications, sexual dysfunction, sleep disturbance) that can negatively impact quality of life, yet are rarely addressed in routine nephrology care. The Women Kidney Program (WKP) registry was developed to systematically capture reproductive, sexual, sleep and quality-of-life domains in women with kidney disease to inform care and future interventions.
We established an ongoing, IRB-approved observational registry of biological females ≥18 years, with kidney disease or kidney transplant, recruited at the M Health Fairview nephrology clinic. Chart abstraction captured demographics, CKD stage and characteristics, imaging, comorbidities, and medications. Patient-reported outcomes included the Menopause Rating Scale (MRS), Female Sexual Function Index (FSFI), PROMIS-Sleep Short Form, and quality of life scale (QOLS). Enrollment began in May 2024; this analysis includes data accrued through September 2025. Complete case analyses were performed on participants with full baseline data.
We enrolled 97 participants (mean age 55.9 ± 18.2 years); most identified as White (81.8%). Among participants with CKD, stage distribution was: stage 1 (7.8%), 2 (13.0%), 3a (31.2%), 3b (32.5%), 4 (13.0%), and 5 (2.6%). Common etiologies included lupus nephritis (19.6%), diabetic kidney disease (12.4%), hypertensive nephropathy (12.4%), and nephrolithiasis (12.4%). Proteinuria at diagnosis was documented in 36.4%; hypertension and diabetes were present in 72.1% and 36.0%, respectively. The most recent estimated glomerular filtration rate by creatinine was 55.3 ± 25 mL/min/1.73 m². The time from kidney disease diagnosis to first nephrology visit averaged 3.25 ± 5.74 years. Regarding kidney‑relevant women’s health, 62.8% reported a prior pregnancy; preeclampsia and gestational diabetes occurred in 9.6% and 3.6%, respectively. Postmenopausal status was reported by 77.6%. After kidney disease diagnosis, 13.4% had ≥1 pregnancy and 10.3% had ≥1 live birth. Social support was often limited (6.0% none; partner as main support 49.5%). FSFI, MRS, and PROMIS‑Sleep scores indicated substantial burdens across sexual desire and lubrication, genitourinary syndrome of menopause symptoms, and sleep quality (Figure 1). Sexual dysfunction by FSFI (total <26.55; higher=better) was present in 89.2% of all participants.
WKP registry demonstrates high, kidney-relevant symptom burden and actionable care gaps- including lengthy delays to specialty care, and infrequent documentation of women’s health history across CKD stages 1-5. Findings support routine screening for menstrual/menopausal history, sexual function, and sleep; structured referral pathways (OB‑GYN/menopause, pelvic floor/sexual medicine, sleep); and prospective evaluation of targeted interventions stratified by CKD stage and etiology.
