COMPARATIVE ANALYSIS OF 16G AND 18G NEEDLES IN RENAL BIOPSY - CORE ADEQUACY AND SAFETY OUTCOMES

 

Certificate Output Instructions

For best output, select "Paper Size" as "A4" and "Margin" as "0" or "None".

To save or print to PDF, please select Print Destination > Save as PDF, enable Background Graphics under "More Settings", then click "Save".

 


 

Certificate Background

   

Presented the abstract " "
(Abstract co-author(s):  )

 

 

E-Poster Presentation

During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center. 

Preparing your E-Poster

Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.

​E-Poster Submission Deadline

Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.​

E-Poster Format Requirements
  • PDF file
  • Layout: Portrait (vertical orientation)
  • One page only (Dim A4: 210 x 297mm or PPT)
  • E-Poster can be prepared in PowerPoint (one (1) PowerPoint slide) but must be saved and submitted as PDF file.
  • File Size: Maximum file size is 2 Megabytes (2 MB)
  • No hyperlinks, animated images, animations, and slide transitions
  • Language: English
  • Include your abstract number
  • E-posters can include QR codes, tables and photos
 
COMPARATIVE ANALYSIS OF 16G AND 18G NEEDLES IN RENAL BIOPSY - CORE ADEQUACY AND SAFETY OUTCOMES

Please follow the instructions below to input your abstract title.

Abstract titles should be brief and reflect the content of the abstract.

  • The title will not be accepted if it exceeds 25 words.
  • Type in CAPITAL LETTERS.
  • Lowercase may be used for abbreviations only, for example, mRNA.
Amit Kumar
Mohanty
Amit Kumar Mohanty write4amit@gmail.com Asian Institute of Nephrology and Urology Hyderabad India Nephrology Hyderabad India *
Srikanth Gundlapalli srikanthnephro@gmail.com Asian Institute of Nephrology and Urology Hyderabad India Nephrology Hyderabad India -
Sujeeth Reddy Bande sujeethbande@gmail.com Asian Institute of Nephrology and Urology Hyderabad India Nephrology Hyderabad India -
Venkateswar Rao Mulpuru mulpuru1962@gmail.com Asian Institute of Nephrology and Urology Hyderabad India Nephrology Hyderabad India -
 
 
 
 
 
 
 
 
 
 
 

Percutaneous renal biopsy remains the gold standard for diagnosing renal pathologies. The choice of needle gauge significantly influences both diagnostic yield and procedural safety. Larger gauge needles, such as 16G, are believed to provide better tissue adequacy, whereas 18G needles are considered safer. This study compares the core adequacy and safety outcomes of 16G and 18G needles in native and allograft kidney biopsies.

Core adequacy was evaluated in a combined prospective and retrospective cohort (n=611), while safety outcomes were assessed in a purely prospective cohort (n=402). All biopsies were conducted at a single centre over a period of 18 months. Needle selection was based on operator assignment. Standardized pre-biopsy laboratory screening, real-time core evaluation, and structured post-biopsy monitoring were followed. Core adequacy was defined as; Native kidney (LM): ≥10 glomeruli, Native kidney (IF): ≥1 glomerulus, Allograft (LM): ≥7 glomeruli and ≥2 arteries. Complications were stratified by severity and analyzed using SPSS. A p-value < 0.05 was considered statistically significant.

The study case selection and distribution is as per the flow diagram.

study flow diagram and patient distribution

Baseline characteristics for Complications data

Out of 611 biopsies (16G: n=235; 18G: n=376), core adequacy was significantly higher in the 16G group (93.33%) compared to the 18G group (81.38%), p<0.0001. Mean glomerular yield per core was also significantly greater with 16G (13.36 ± 3.81) than 18G (8.43 ± 3.96), p<0.0001. Arterial yield per core was significantly higher in the 16G group (1.69 ± 0.58 vs. 0.85 ± 0.22), p<0.0001. Cores with no diagnostic yield were significantly lower in the 16G group (1.38%) compared to the 18G group (4.73%), p = 0.0026. 

Among the 402 patients analyzed prospectively for complications (16G: n=215; 18G: n=187), overall complication rates were comparable (16G: 16.74%, 18G: 18.18%). Moderate (16G: 1.40%, 18G: 2.14%) and Severe (16G: 0.47%, 18G: 1.07%) complications were rare and not significantly different between the two groups.Notably, the 16G group had more baseline bleeding risk factors, including higher creatinine and lower platelet counts, yet did not show a higher complication rate.

The 16G biopsy needle demonstrates superior core adequacy and glomerular yield without increasing the incidence of bleeding-related complications compared to the 18G needle. These results support the preferential use of 16G needles for renal biopsies when optimal tissue adequacy is clinically important.

The content presented in this abstract was submitted for APCN x TSN 2025. Re-submitting the abstract is permitted by the organizers of the original meeting and written NOC certificate was obtained.

Kewords