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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Ambient air pollution-attributable deaths exceed 4 million annually and 89% of these occur in low- and middle- income countries (LMIC). Although epidemiological evidence on air pollution and kidney disease is emerging globally, there is a disparity in the quantity and quality of existing epidemiological studies arising from developed countries compared to less developed countries. The aim of this study was determine the association between long-term exposure to ambient air pollution and chronic kidney disease risk.
A comparative cross-sectional study of communities in two Nigerian States, representing exposed and less exposed groups. The sample size after adding a 20% attrition rate was 550 per group. The exposed sample was drawn from two communities situated near petrochemical industries in Delta State while communities in Ondo State served as the comparator. Consenting adults aged 15-59 years who had lived for at least five years in the selected communities were included.
Sociodemographic and clinical data included age, sex, level of education, annual income, occupational status, habits, chemical exposures, comorbidities (hypertension, diabetes, obesity), weight, height, waist circumference, waist-hip ratio, and blood pressure. Laboratory investigations included urine dipstick, urine albumin:creatinine ratio (ACR), serum creatinine, random blood sugar, serum C-reactive protein (CRP), myeloperoxidase (MPO) and malondialdehyde (MDA).
Mean concentrations of air pollutants, namely particulate matter (PM2.5, PM10), carbon monoxide (CO), carbon dioxide (CO2), nitrogen dioxide (NO2) and volatile organic compounds (VOC), were measured over 6 months duration in partnership with community volunteers, to establish current air quality.
Data was analysed using IBM SPSS for Windows, version 27.
544 and 380 participants have been enrolled for the exposed and less-exposed group respectively; recruitment and data collation are ongoing. Complete data for 440 and 212 participants in the exposed and less-exposed group respectively, were analysed.
Mean age was 44.56 ±12.56 years and females constituted 74.7% of the participants. Prevalence of CKD was 13.9% (95%CI: 10.7-17.1) in the exposed group; 11.4% had eGFR <60ml/min while 3.4% had severely increased urine ACR (>30mg/mmol). Nine out of 10 participants (90.5%) had moderately increased urine ACR (3-30mg/mmol). In contrast, prevalence of CKD was 5.7% (95%CI: 2.6 - 8.8) in the less-exposed group; 3.8% had eGFR <60ml/min while 2.7% had severely increased urine ACR. Similarly, 9 out of 10 participants (92.7%) had moderately increased urine ACR (3-30mg/mmol)
The mean concentrations of inflammatory markers were not statistically significantly different between participants with and without CKD in the exposed group. A higher percentage of participants in the exposed communities had elevated serum MPO (42.6% vs. 16.6%, p=<0.001) and CRP (18.9% vs. 13.4%, p=0.078) than those in the less-exposed communities. Serum MDA was elevated in 70.6% and 76.7% of participants in the exposed and less-exposed groups respectively (P=0.098)
Lastly, the mean concentration of PM2.5, PM10, NO2 and CO2 exceeded the World Health Organization’s recommended acceptable limits while CO, VOC and O3 were within acceptable limits in the exposed community.
Some criteria air pollutants remain high in communities near petrochemical refineries. The prevalence of CKD in these communities was more than two-folds the prevalence in less-exposed communities. A higher proportion of people residing near petrochemical industries had elevated systemic inflammatory markers than the less-exposed people. However, our preliminary findings show that these inflammatory markers were not associated with CKD.
Lastly moderately increased urine ACR was extremely prevalent in the study population, however, the clinical significance or associated health risk is unclear. The current risk classification of urine ACR may need to be reconsidered in specific populations.
