Back
For best output, select "Paper Size" as "A4" and "Margin" as "0" or "None".
To save or print to PDF, please select Print Destination > Save as PDF, enable Background Graphics under "More Settings", then click "Save".
During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Chronic kidney disease (CKD) remains a leading cause of premature mortality among people living with HIV (PLHIV). Despite integrated HIV–NCD management, Tanzanian HIV guidelines still define “high-risk” age for CKD screening as ≥50 years. Growing evidence suggests that kidney aging in HIV begins earlier, driven by metabolic, viral, and drug-related factors. This study evaluated age-related incidence and predictors of CKD among PLHIV at a tertiary centre in Northern Tanzania.
We conducted a retrospective cohort of PLHIV enrolled at the KCMC Care and Treatment Centre between 2011 and 2019 and followed for five years. Participants with normal baseline kidney function were included. CKD was defined as two consecutive eGFR values below 60 mL/min/1.73 m² at least three months apart, using the CKD-EPI 2021 formula. Multivariable logistic regression identified independent predictors at 95 % confidence and p<0.05.
Among 544 participants (69.8 % female; median age 38 years), the CKD incidence was 14.5 per 1000 person-years, rising sharply with age from 7.2 (<40 years) to 21.4 (40–49 years) and 26.6 (≥50 years). In adjusted analysis, individuals aged 40–49 years had nearly fourfold higher odds of CKD (aOR 3.9, 95 % CI 1.2–9.8, p<0.01). Hypertension (aOR 4.9, 95 % CI 2.1–11.5, p<0.001), tenofovir use (aOR 2.2, p=0.016), and poor ART adherence (aOR 5.1, p=0.005) were also significant predictors.
CKD risk among PLHIV accelerates as early as the fourth decade of life, preceding current guideline thresholds. These findings provide evidence for lowering the “high-risk” age cut-off to ≥40 years. Incorporating early renal screening, hypertension control, and tenofovir stewardship into HIV programs could reduce preventable kidney failure and premature deaths in sub-Saharan Africa. These findings underscore the urgency of redefining HIV-CKD screening thresholds to age ≥40 years across sub-Saharan Africa.
