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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
In much of sub-Saharan Africa, neonatal acute kidney injury (AKI) is largely underdiagnosed, with up to 99 % of affected neonates failing to receive kidney replacement therapy (KRT). Consequently, the long-term risks of chronic kidney disease (CKD), hypertension, and mortality remain poorly characterized. Addressing this knowledge gap is critical to improving early detection, guiding interventions, and reducing the future burden of kidney-related noncommunicable diseases in this high-risk population.
This prospective study enrolled neonates admitted to level-three neonatal units across five tertiary hospitals in Nigeria. AKI was defined and staged using the modified neonatal KDIGO criteria, with eGFR estimated by the U25 equation. CKD was diagnosed based on serial serum creatinine, total urine protein-to-creatinine ratio, and kidney structural abnormalities. Participants were systematically followed at discharge, 1, 3, and 6 months, and annually thereafter to assess renal function, growth, and clinical outcomes. Key outcomes included persistent proteinuria, CKD development, need for dialysis, mortality, and growth failure, providing a comprehensive evaluation of the long-term impact of neonatal AKI.
Of the 106 children followed at a median age of 2.0 years (interquartile range [IQR] 1.7–4.0), 52.8% were term and the male to female ratio was 1.5 to 1. Median age at admission was 4 hours (IQR 1–33). Mean gestational age was 35.5±4.2 weeks, mean weight 2426±881.8 gm, mean length 44.66±6.03 cm and mean occipitofrontal circumference was 32.22±3.41cm. Pregnancy induced hypertension occurred in 15.3% and oligohydramnios in 10.4%. Caesarean delivery occurred in 53.8%. Congenital anomalies of the kidney and urinary tract occurred in 12.3%. Severe perinatal asphyxia occurred in 39.6% and 55.7% presented with respiratory distress. Oxygen therapy was required in 67.0% and continuous positive airway pressure in 23.6%. Preterm births accounted for 47.2%; among them, 74.0% received antenatal corticosteroids, 47.0% received KMC and 41.2% caffeine citrate. Neonatal acute kidney injury occurred in 34.9%. Mortality was higher in infants with neonatal AKI at 13.5% compared with 1.5% in those without acute kidney injury (p=0.03). At a median follow up of 2.0 years, 33.0% had reduced eGFR and 40.0% of them had a history of neonatal acute kidney injury.
Neonatal acute kidney injury is a common complication in low- and middle-income countries and is associated with higher mortality and intermediate outcomes, including reduced kidney function.
