Back
For best output, select "Paper Size" as "A4" and "Margin" as "0" or "None".
To save or print to PDF, please select Print Destination > Save as PDF, enable Background Graphics under "More Settings", then click "Save".
During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Acute Kidney Injury (AKI) is a frequent and life-threatening complication in critically ill patients. Continuous Renal Replacement
Therapy (CRRT) provides hemodynamic stability for unstable cases but remains difficult to sustain in low- and middle-income
countries (LMICs) because of high consumable costs and limited trained staff. Evidence from Nigerian ICUs is sparse. This study
evaluated utilization patterns, anticoagulation practices, and short-term outcomes of CRRT and hybrid modalities in a resource-limited tertiary ICU
A retrospective descriptive study was conducted at the Regions Healthcare ICU and Dialysis Unit, Nigeria. Adults (≥18 years)
managed with CRRT or Sustained Low-Efficiency Dialysis (SLED) between January 2023 and June 2025 were included. Data captured
demographics, comorbidities, indications, modality, anticoagulation, filter lifespan, downtime, delays, and outcomes. Renal recovery
followed Acute Disease Quality Initiative and KDIGO criteria, defined as dialysis independence with improving urine output and
serum creatinine within 14 days and was categorized as complete (return to baseline), partial (independence with residual
impairment or later intermittent dialysis), or none (CRRT-dependence or death). Descriptive and chi-square analyses assessed
relationships between delay type, renal recovery, and ICU survival. Ethical approval was obtained with consent waived.
Eighty-six patients met inclusion criteria (64% male; mean ± SD 63.7 ±
16.8 years; range 25–92). Major comorbidities were hypertension 59.3 %,
CKD 50%, and diabetes 29.1%. Sepsis was the leading diagnosis (80.2%),
followed by AKI on CKD precipitated by sepsis (40.7%) and stroke (10.5%).
Indications for therapy included uremia/azotemia (87.2%), hemodynamic
instability (73.3%), and acid–base imbalance (26.7%). SLED was most
common (57%), CVVHDF 22.1%, CVVHD 20.9%. Heparin was used in 93 %.
Mechanical ventilation and vasopressor support were required in 55.8 %
and 54.7 %, respectively. Circuit turnover was mainly end-of-session
(54.7%), with clotting (14 %) and clogging (23.3 %) as premature causes.
Downtime stemmed from patient-care activities (76.7 %) and
hemodynamic instability (15.1 %). Dialysis initiation was delayed in 42
patients (48.8%), chiefly for financial (73.8 %), logistical (23.8 %), and
staff-related (2.4%) reasons. Median time to dialysis was 18 h (IQR 12–24)
for non-delayed vs 46 h (IQR 36–72) for delayed. Delay category showed
borderline association with renal recovery (χ² p = 0.049). Overall renal
recovery was 70.9%, and ICU mortality 50%. Median filter lifespan 8 h
(IQR 6–12).
This first Nigerian ICU CRRT cohort demonstrates encouraging renal recovery despite high mortality, reflecting critical-illness severity
and systemic barriers. Financial constraints predominated as causes of treatment delay, while circuit failure and workflow
interruptions reduced efficiency. Improving outcomes requires policy-level cost subsidies, standardized local protocols, and ongoing
staff training. Future studies should evaluate cost-reduction strategies, safe circuit reuse, and predictive models suited to resourcelimited ICUs. These findings provide a foundation for scalable CRRT implementation across LMICs.
Keywords:
CRRT, SLED, AKI, Renal Recovery, Resource-Limited ICU, Nigeria, Critical Care
