Renal replacement therapy in the patient with acute kidney injury

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Renal replacement therapy in the patient with acute kidney injury

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Co-author 1

Narantungalag Bayankhuu Narantungalagbayankhuu@gmail.com Orkhon province Hospital Department of Internal Medicine Orkhon province Mongolia *

Co-author 2

Saruultuvshin Adiya sarulaadiya@gmail.com Mongolian National University of Medical Sciences, Mongolia Japan Hospital Department of Internal Medicine Ulaanbaatar city Mongolia -

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Introduction

Acute kidney injury (AKI) is a life-threatening condition characterized by a rapid decline in kidney function over a short period of time. Our study aims to determine the clinical results of hemodialysis (HD) treatment performed on acute kidney injury (AKI) patients at Orkhon province hospital of Mongolia over the period of 15 years, and to identify the influencing factors. Continuous renal replacement therapy (CRRT) has not yet initiated in rural area in Mongolia.

Methods

Quantitative and qualitative analyses are done based on the medical archive, medical history data from November 20, 2009 to August 1, 2025. We studied the effectiveness of those HD treatment and analyzed the factors such as age, gender, cause, number of HD sessions.

Results

We have provided HD treatment for a total of 827 patients. 679 were chronic kidney disease patients who maintained on HD. 148 were AKI patients who required HD. Out of those, 112 AKI patients (82 males and 30 females) were enrolled in this study. The mean age was 49.8 year. 83% of the patients recovered from AKI with HD treatment and showed improvement in kidney function. Deceased patients accounted 17%. The main causes of those deceased were delayed visit to hospital, severity of patient's condition, and presence of multiple organ failure. The leading cause of AKI was alcohol intoxication (46.4%), followed by drug-induced (10.7%), sepsis (9.8%), chemotherapy induced (8%), Crush syndrome (4.5%), acute pancreatitis (4.5%) and others (16.1%). Most patients (76.8%) recovered after 1-5 HD sessions, and some of them (16.8%) recovered after 6-10 HD sessions, however in severe cases (6.4%), more than 10 sessions were needed.

Conclusion

Our study shows that HD is essential treatment option for those with AKI. Further, CRRT is necessary in severe AKI patients in rural area in our country.

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