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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
SSc is an autoimmune that involves skin and internal organs, including kidneys. SRC is one of the most severe complications. It’s a syndrome characterized by a rapid decline in renal function, hypertensive emergency and TMA presence. SRC prevalence is low (2.6-12 cases per million inhabitants) and highly mortal if not promptly treated.
We report the case of a 49-year-old woman with 1 year history of diffuse SSc (lung, skin and joint affection), without kidney disease. She presented to the emergency department due to dyspnea of 2 weeks´ duration with fatigue, hyperthermia and anuria associated. Laboratory results demonstrated the need for urgent RRT. Table 1 provides a summary of the patient’s clinical and biochemical features.
Chest CT revealed associated interstitial lung disease, pleural and pericardial effusion. Figure 1 shows skin lesions and CT/ renal biopsy findings. Immediate antihypertensive therapy with captopril was initiated, along with renal replacement therapy, requiring up to three anihypertensive agents.
The immunosuppressive therapy was temporarily suspended until an infectious process could be ruled out. During her hospital course, she required intermittent acute hemodialysis sessions, with a rising BUN/creatinine trend, and persistent anuria, necessitating chronic renal replacement therapy. After a 1-month hospitalization, the patient died from pulmonary embolism.
Scleroderma renal crisis (SRC) is a rare complication of systemic sclerosis, more frequent in the diffuse form, which can rapidly progress to acute kidney injury, need for renal replacement therapy, and death. Timely diagnosis requires clinical correlation with systemic sclerosis, exclusion of other thrombotic microangiopathies, and, when feasible, histological confirmation via renal biopsy. Early initiation of ACE inhibitors, particularly captopril, improves short-term survival but does not guarantee renal recovery in all cases, highlighting the clinical heterogeneity and the need for predictive biomarkers and more effective therapeutic strategies.
