Exploratory Study on Patient-Important Outcomes Among Japanese Peritoneal Dialysis Patients

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Exploratory Study on Patient-Important Outcomes Among Japanese Peritoneal Dialysis Patients

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Co-author 1

Yudo Tanno yudo@msd.biglobe.ne.jp The Jikei University School of Medicine Division of Nephrology and Hypertension, Department of Internal Medicine Tokyo Japan *

Co-author 2

Yukio Maruyama maruyama@td5.so-net.ne.jp The Jikei University School of Medicine Division of Nephrology and Hypertension, Department of Internal Medicine Tokyo Japan -

Co-author 3

Nanae Matsuo nana77m@jikei.ac.jp The Jikei University School of Medicine Division of Nephrology and Hypertension, Department of Internal Medicine Tokyo Japan -

Co-author 4

Masato Ikeda jikemasa@jikei.ac.jp The Jikei University School of Medicine Division of Nephrology and Hypertension, Department of Internal Medicine Tokyo Japan -

Co-author 5

Takashi Yokoo tyokoo@jikei.ac.jp The Jikei University School of Medicine Division of Nephrology and Hypertension, Department of Internal Medicine Tokyo Japan -

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Introduction

The Standardized Outcomes in Nephrology–Peritoneal Dialysis (SONG-PD) initiative identified a set of core outcomes for peritoneal dialysis (PD) patients. However, the original study included very few Japanese participants, raising concerns about the applicability of these findings to Japanese PD populations. This study aimed to determine which outcomes from the SONG-PD list are most valued by Japanese PD patients.

Methods

We enrolled 199 patients (mean age, 61 ± 12 years; 71.9% male) who initiated PD between January 1, 2018, and September 30, 2024. Patient-important outcomes were assessed using a structured questionnaire, and clinical data were extracted from medical records. The relative importance of each outcome was compared with the international SONG-PD results.

Results

The outcomes most frequently prioritized by Japanese PD patients were “Flexibility with time,” “Life participation” (e.g., ability to work, study, or perform home duties), “Mobility/fitness,” and “Ability to travel.” While “Life participation” overlapped with the SONG-PD core outcomes, the others differed, indicating potential cultural or contextual distinctions. Subgroup analyses showed that “Death” received higher priority among patients with diabetic nephropathy compared to those without, and modest variations were observed between younger and older patients.

Conclusion

Japanese PD patients place high value on maintaining flexibility, independence, and social engagement in daily life. These preferences suggest that international core outcomes may not fully reflect patient priorities in Japan. Incorporating individualized, goal-oriented outcome measures into PD care may better support shared decision-making and patient-centered treatment planning.

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