ASSESSMENT OF FRAILTY AND CLINICAL OUTCOMES IN ELDERLY PATIENTS WITH ACUTE KIDNEY INJURY USING FRAIL SCALE

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ASSESSMENT OF FRAILTY AND CLINICAL OUTCOMES IN ELDERLY PATIENTS WITH ACUTE KIDNEY INJURY USING FRAIL SCALE

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Co-author 1

Soyoung Lee 20160081@eulji.ac.kr Eulji Medical Center, Eulji University School of Medicine Department of Internal Medicine Daejeon Korea (Republic of) *

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Introduction

Frailty in elderly population is associated with increased morbidity. Acute kidney injury (AKI) occurs frequently increased with age. Pre-existing frailty is acknowledged as an independent risk factor for AKI and mortality. However, frailty in non-dialysis-requiring AKI and renal recovery had not been discussed in the literature.

This study aims to evaluate the clinical profile and outcomes of AKI in elderly in association with FRAIL scale. FRAIL scale consists of five short-question assessments of fatigue, resistance, aerobic capacity, illnesses and loss of weight.

Methods

This was a single center prospective observational study. We collected 10 cases of AKI patients who aged 65 or greater, FRAIL scale, hospital day, Body Mass Index (BMI), renal recovery was assessed from medical record. Robust (FRAIL score 0) and Pre-frail (FRAIL scale 1-2) patients were categorized as the non-frail group. Patients with FRAIL scale of 3-5 were categorized as the frail group.

Results

Out of 10 patients, 6 (60%) were female with mean age of 77.2 years and mean BMI was 23.9kg/m2. The mean hospital day was 9 days. Comparison of renal recovery among non-frail and frail group revealed significantly low renal recovery in frail group (p=0.04, Fisher’s exact test).

Conclusion

This study indicates pre-existing frailty is closely associated with renal recovery and also enlightens that simple questionnaire-based frailty assessment as FRAIL scale can be a tool to predict renal recovery. Further investigation with large-scale studies is needed to validate this observation.

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