IMPLEMENTATION OF PHARMACIST-LED CHRONIC KIDNEY DISEASE SCREENING IN AUSTRALIAN COMMUNITY PHARMACIES: BASELINE DATA ANALYSIS

 

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IMPLEMENTATION OF PHARMACIST-LED CHRONIC KIDNEY DISEASE SCREENING IN AUSTRALIAN COMMUNITY PHARMACIES: BASELINE DATA ANALYSIS

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Ayana
Korsa
Ayana Korsa akor6759@uni.sydney.edu.au The University of Sydney Sydney Pharmacy School Sydney Australia *
Ines Krass ines.krass@sydney.edu.au The University of Sydney Sydney Pharmacy School Sydney Australia -
Kamal Sud kamal.sud@sydney.edu.au The University of Sydney Nepean Clinical School Sydney Australia -
David Johnson david.johnson@uq.edu.au The University of Queensland Centre for Health Services Research Brisbane Australia -
Sanjyot Vagholkar sanjyot.vagholkar@mqhealth.org.au Macquarie University MQ Health General Practice Sydney Australia -
Rita McMorrow rita.mcmorrow@unimelb.edu.au The University of Melbourne Department of General Practice and Primary Care Melbourne Australia -
Lukas Kairaitis Lukas.Kairaitis@health.nsw.gov.au Blacktown Mount Druitt Hospital Department of Renal Medicine Sydney Australia -
Judy Mullan jmullan@uow.edu.au University of Wollongong Graduate School of Medicine Wollongong Australia -
Anh Tran a.tran@sydney.edu.au The University of Sydney NHMRC Clinical Trials Centre Sydney Australia -
Connie Van connie.van@sydney.edu.au The University of Sydney Sydney Pharmacy School Sydney Australia -
Wubshet Tesfaye w.tesfaye@uq.edu.au The University of Queensland School of Pharmacy and Pharmaceutical Sciences Brisbane Australia -
Natasa Gisev n.gisev@unsw.edu.au UNSW National Drug and Alcohol Research Centre Sydney Australia -
Breonny Robson breonny.robson@kidney.org.au Kidney Health Australia GM Clinical & Research Melbourne Australia -
Ronald Castelino ronald.castelino@sydney.edu.au The University of Sydney Sydney Pharmacy School Sydney Australia -
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The Chronic Kidney Disease Screening and Quality Use of Medicines (CKD-QUM) trial, conducted through community pharmacies located in kidney failure hotspot areas, aimed to improve CKD detection and optimise medication use in Australia. In this analysis, we describe participants’ baseline characteristics and compare CKD risk factors with estimates from the National Health Measures Survey (NHMS, 2011–2012). 

Eligible participants were aged 35–74 years and had one or more CKD risk factors. The QKidney® risk tool was used in combination with blood pressure (BP) levels to stratify patients’ 5-year CKD risk as low, moderate or high. Point-of-care (POC) testing of serum creatinine concentration to estimate the glomerular filtration rate (eGFR) was performed in the intervention arm among participants at moderate-to-high risk. The prevalence of CKD risk factors and reduced kidney function was compared with NHMS data. Data were organised in Excel and analysed in SPSS (version 31 for Windows) using descriptive statistics. 

Of the 1,485 participants recruited over two years, 1,193 were included in this analysis (552 [46.3%] in the intervention arm and 641 [53.7%] in the control arm). Most participants were from metropolitan areas (61%) and were female (56.2%), while 3.5% identified as First Nations people. The mean (±SD) age was 61.3±9.8 years and the mean (±SD) BMI was 30.5±6.6 kg/m2. Compared with NHMS estimates, trial participants had a significantly higher prevalence of being overweight/obese (82%, 95% CI 80–84 vs 60.5%, 95% CI 56–65), hypertension (70%, 95% CI 68–73 vs 34.1%, 95% CI 29.8–38.4) and diabetes (38%, 95% CI 35–40 vs 16.2%, 95% CI 13.5–18.9). Overall, 68% of trial participants were at moderate-to-high risk of CKD (58.6% by QKidney®; 30.5% by BP). Among the 400 moderate-to-high risk participants in the intervention arm, 84 (21%) had reduced kidney function (eGFR <60 mL/min/1.73 m2) on POC testing—substantially higher than the national estimate (5.2%, NHMS 2022–2024).

This analysis demonstrated that targeted screening in community pharmacies effectively identified patients at risk of developing CKD, providing an opportunity to enhance early detection and implement interventions such as optimising medication use through pharmacist counselling. 

Disclosure: This abstract has also been submitted and accepted for oral presentation at the Australasian Pharmaceutical Science Association (APSA) Annual Conference, to be held in Adelaide, Australia, from 7 to 10 December 2025.  

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