POCUS BEFORE DIALYSIS: A NEW WINDOW INTO VASCULAR AND TISSUE CONGESTION

 

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https://storage.unitedwebnetwork.com/files/1099/f65ea48024ab88b176438ec996a6bb09.pdf
POCUS BEFORE DIALYSIS: A NEW WINDOW INTO VASCULAR AND TISSUE CONGESTION

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Mariana
Zavala-Gómez
Mariana Zavala-Gómez mariana.zavala@udem.edu Hospital Universitario Dr. José Euleterio González Nephrology Monterrey Mexico *
Paola Borbolla-Flores pborbollaf@gmail.com Hospital Universitario Dr. José Euleterio González Nephrology Monterrey Mexico -
Ricardo Garza-Treviño ricardogarza1999@gmail.com Hospital Christus Muguerza Internal Medicine Monterrey Mexico -
Juan Pablo Gómez-Villarreal dr.jpgv@gmail.com Hospital Universitario Dr. José Euleterio González Nephrology Monterrey Mexico -
Mara Olivo-Gutiérrez mara_olivo84@hotmail.com Hospital Universitario Dr. José Euleterio González Nephrology Monterrey Mexico -
Lilia Rizo-Topete dra.liliarizo@gmail.com Hospital Universitario Dr. José Euleterio González Nephrology Monterrey Mexico -
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Point-of-care ultrasound (POCUS) is an emerging bedside modality that augments the physical examination and provides real-time hemodynamic data. Assessment of volume status is particularly challenging in hemodialysis patients because conventional clinical markers and dry-weight estimation by bioimpedance may not reliably reflect effective extracellular volume. We evaluated the utility of a focused POCUS protocol performed immediately prior to hemodialysis to detect sonographic markers of vascular and tissue congestion.

We performed a prospective observational study in a chronic hemodialysis unit. Consecutive prevalent patients on maintenance hemodialysis underwent a standardized pre-dialysis POCUS protocol including lung ultrasound (B-lines and pleural effusion), focused cardiac ultrasound (pericardial effusion, estimation of LVEF by AI-assisted algorithm), and portal vein pulsatility variation (PVPV) as a marker of systemic venous congestion. Demographic, clinical, and bioimpedance dry-weight data were recorded. Descriptive statistics are reported as mean ± SD or median (IQR) as appropriate. The study protocol was approved by the local ethics committee and all patients provided informed consent.

This is only a preview of this protocol. Eight prevalent hemodialysis patients were included (mean age 42.9 ± 18.4 years; 87.5% male). All had tunneled right internal jugular vascular access; 75% had CKD G5. Mean dry weight 70.7 ± 17.9 kg; pre-dialysis weight 71.4 ± 18.3 kg; median interdialytic weight gain 2.9 kg (IQR 1.9–3.2). Despite most patients being at or near estimated dry weight by bioimpedance, 100% exhibited a B-line pulmonary pattern and 75% had pulmonary congestion in >4 lung quadrants. Pleural effusion occurred in 25% and pericardial effusion in 12.5%. Median AI-estimated LVEF was 49% (IQR 41–54). Portal vein pulsatililty >30% was found in 87.5%, with a median 33.5% (IQR 28.5–46), consistent with mild–moderate venous congestion. Mean systolic/diastolic BP were 145/82 mmHg; mean HR 73 bpm; SpO₂ 95%. Notably, 87.5% of patients were asymptomatic for fluid overload.  Figure 1. 

This pre-dialysis POCUS protocol detected frequent subclinical pulmonary and systemic venous congestion in hemodialysis patients, even when bioimpedance-based dry weight suggested euvolemia in some patients. These findings imply that conventional dry-weight assessment may underestimate effective extracellular volume in some patients and support routine incorporation of lung and hemodynamic ultrasound into pre-dialysis evaluation to optimize volume management. This is only a preview and a small sample; data collection is ongoing to validate these preliminary observations and to establish clinically applicable congestion thresholds for the hemodialysis population.

Kewords