ULTRASONOGRAPHIC, CLINICAL AND BIOCHEMICAL EVALUATION OF CHRONIC KIDNEY DISEASE IN A WORLD KIDNEY DAY CAMPAIGN IN PERU

 

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https://storage.unitedwebnetwork.com/files/1099/c787a91182ed6f93ef8bf3dec89eb75b.pdf
ULTRASONOGRAPHIC, CLINICAL AND BIOCHEMICAL EVALUATION OF CHRONIC KIDNEY DISEASE IN A WORLD KIDNEY DAY CAMPAIGN IN PERU

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Katia Olga Teresa
Hernandez Torres
Katia Olga Teresa Hernandez Torres katia302019@gmail.com Hospital Nacional Dos de Mayo Lima Lima Peru *
Juan Oscar Lluncor Vasquez jlluncor@upch.edu.pe Hospital Nacional Dos de Mayo Lima Lima Peru -
Paola Franchesca Segura Seminario coordmedico@kidneycare.com.pe Hospital Nacional Dos de Mayo Lima Lima Peru -
Maria del Rosario Llamas Barbaran rosario.llamas.barbaran@gmail.com Hospital Nacional Dos de Mayo Lima Lima Peru -
Fernando Alberto Mayor Balta fernandoalbmayor@gmail.com Hospital Nacional Dos de Mayo Lima Lima Peru -
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Chronic Kidney Disease (CKD) represents a major public health problem in Peru, being the fourth leading cause of death and disability, affecting nearly 4 million people. Early diagnosis is difficult because it is often asymptomatic in its early stages. In the context of World Kidney Day 2025, ¿under the slogan “Are your kidneys ok?", a kidney health assessment campaign was carried out in a Peruvian national hospital, involving the nursing and nutrition teams, with the aim of promoting early detection of CKD and facilitating equitable access to medical services. The overall objective was to detect early signs of CKD and evaluate the correlation between clinical, biochemical, and ultrasound findings. Specific objectives included identifying risk factors, describing renal ultrasound findings, promoting kidney health awareness, and guiding patients with signs suggestive of CKD toward appropriate nephrological follow-up.

education talksurine testAn observational, descriptive-analytical, cross-sectional and prospective study was conducted during World Kidney Day, with a sample of 94 patients treated at Hospital (Lima). The evaluation included measurement of fasting blood glucose and blood pressure, urine test with a dipstick, renal ultrasound, nephrology consultation and educational talks by nursing and nutritionists. Statistical tests were used to analyze correlations (Pearson or Spearman according to normality), association between categorical variables (Chi square) and group comparison (Mann-Whitney U), using the JASP 0.19.3.0 software.

The mean age of the sample was 56 years,with a predominance of women. Hypertension was present in 23.4% of the patients, and type 2 diabetes mellitus in 17.0%; 3.2% had a previous diagnosis of CKD. Urine tests revealed no albuminuria in 53.2% of the patients, while 37.2% had mild albuminuria, 4.2% moderate albuminuria, and 1.1%seriousThe predominant urinary pH was 6 (59.6%).The most frequent urinary density was 1010 and 1020, and glycosuria was absent in 91.5%.

Renal ultrasound measurements showed consistent medians for length, transverse diameter andcortical thicknessin both kidneys.

No significant correlation was found between albuminuria and renal ultrasound measurements. (rho close to 0, p > 0.10). In contrast, ultrasound measurements showed significant positive correlations with each other (rho from 0.227 to 0.836, p < 0.05), indicating anatomical coherence. Albuminuria was not related to urinary variables such as pH, hemoglobinuria, density or glycosuria. A significant negative correlation between hemoglobinuria and urinary density stood out (rho = -0.390, p < 0.001).

Furthermore, glycosuria was significantly associated with the presence of diabetes (p = 0.001), but not with albuminuria, while clinical variables such as systolic blood pressure and glucose showed significant differences between patients with and without diabetes.

The results show that renal ultrasound measurements maintain a strong anatomical and functional correlation with each other, while albuminuria, a key marker of kidney damage, was not associated with the structural changes detected by ultrasound or with most urinary variables, possibly due to the patients' early stages of CKD or the limited sample size. The association of glycosuria with diabetes and the inverse relationship between hemoglobinuria and urine specific gravity suggest distinct pathways of renal and metabolic alteration that require multidimensional assessment.

These findings reinforce the need for a comprehensive clinical and diagnostic evaluation using multiple parameters for the early detection and effective management of CKD, given that no single marker can fully reflect the complexity of this disease.

Kewords