The Impact of Chronic Kidney Disease on Functional Recovery in Patients with Proximal Femoral Fractures in the Recovery Unit

 

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https://storage.unitedwebnetwork.com/files/1099/9c4b4474811a4ae6084c31a9888c3dc6.pdf
The Impact of Chronic Kidney Disease on Functional Recovery in Patients with Proximal Femoral Fractures in the Recovery Unit

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Hiroki
Yabe
Hiroki Yabe hiroki-y@seirei.ac.jp Seirei Christopher University Department of Physical Therapy Shizuoka Japan *
Aki Tabata 14rp27@g.seirei.ac.jp Seirei Sakura Citizens Hospital Department of Rehabilitation Chiba Japan -
Shintaro Iio s-iio@sis.seirei.or.jp Seirei Hamamatsu City Rehabilitation Hospital Department of Rehabilitation Shizuoka Japan -
Kenjiro Kunieda yabe090@gmail.com Gifu University Graduate School of Medicine Department of Neurology Gifu Japan -
Takashi Shigematsu 11dr@seirei.ac.jp Seirei Hamamatsu City Rehabilitation Hospital Department of Rehabilitation Medicine Shizuoka Japan -
Ichiro Fujishima 11d08@seirei.ac.jp Seirei Hamamatsu City Rehabilitation Hospital Department of Rehabilitation Medicine Shizuoka Japan -
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Falls and fractures associated with declining physical function in chronic kidney disease (CKD) are a significant challenge. Rehabilitation is critical in the recovery process following proximal femoral fractures (PFF), especially in older patients. However, limited evidence exists regarding the influence of CKD on rehabilitation outcomes in this population. This study aimed to investigate the effect of CKD on rehabilitation outcomes in patients with proximal femoral fractures, with a specific focus on Functional Independence Measure (FIM) scores, FIM effectiveness, and FIM efficiency.

A retrospective cohort study was conducted involving 1,832 patients with proximal femoral fractures admitted to Seirei Hamamatsu City Rehabilitation Hospital from 2014 to 2023. Patients were categorized into those with and without renal dysfunction, with CKD stage 3b as the threshold. Patient characteristics, laboratory data, and FIM scores at admission and discharge were analyzed. Analysis of covariance (ANCOVA) was performed to compare FIM at admission and discharge, FIM gain, FIM effectiveness, and FIM efficiency between the two groups, adjusting for age, sex, BMI, Charlson Comorbidity Index (CCI), sodium, potassium, calcium, hemoglobin, CRP, and albumin levels.

Among the 1,832 patients, 342 had renal dysfunction and 1,490 did not. The renal dysfunction group had significantly lower FIM scores both at admission (74.9 ± 20.9 vs. 81.6 ± 22.3, p = 0.02) and discharge (89.1 ± 21.5 vs. 96.6 ± 22.8, p < 0.001). While no significant difference was observed in FIM gain (15.3 ± 10.9 vs. 14.7 ± 11.9, p = 0.22), FIM effectiveness was significantly lower in the renal dysfunction group (0.31 ± 0.26 vs. 0.39 ± 0.32, p = 0.01). FIM efficiency showed no significant difference between the groups (0.35 ± 0.29 vs. 0.33 ± 0.42, p = 0.61)

CKD is associated with poorer functional outcomes in patients with proximal femoral fractures, with significantly lower FIM scores at both admission and discharge, and reduced FIM effectiveness after adjustment for confounders. These findings underscore the need for tailored rehabilitation strategies in patients with renal dysfunction.

Kewords