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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Renal cyst bleeding is a frequent problem in patients with autosomal dominant polycystic kidney disease (ADPKD). However, its frequency in patients with ADPKD at end-stage kidney disease (ESKD) and its effect on progression of ADPKD is unknown.
We investigated the height-adjusted total volume of acute renal intracystic hemorrhage (htARIH) and its association with age or height-adjusted total kidney volume (htTKV) in patients with ADPKD at initiation of dialysis. We also investigated association between htARIH and changes in htTKV or estimated glomerular filtration rate (eGFR) for 5 years before dialysis initiation.
We enrolled 113 patients who initiated dialysis from 2014 to 2024 (37 men, 76 women; mean age: 60.1 ± 10.5 years). The median volume of htARIH was 29.3 ml (interquartile range: 9.1–70.7 ml). Multivariable regression analysis with stepwise elimination revealed that sex, body mass index (BMI), heart rate, Log (eGFR), and Log (htARIH) were significantly associated with age at dialysis initiation. Log (htARIH) was inversely significantly correlated with age at initiation of dialysis (r=-0.34, p=0.0002). Multivariable regression analysis with stepwise elimination revealed that BMI and Log (htARIH) were significantly associated with htTKV at dialysis initiation. Log (htARIH) was significantly correlated with htTKV at initiation of hemodialysis (r=0.43, p<0.0001). Multivariable linear mixed model analysis with stepwise elimination confirmed that diastolic BP and htARIH category were significant factors for htTKV. The htTKV of the patients with greater htARIH were significantly greater (p<0.0001). Multivariable linear mixed model analysis with stepwise elimination confirmed that activated partial thromboplastin time (APTT) was a significant factor for eGFR. The eGFR was not significantly different among the groups stratified by htARIH (p=0.888).
HtARIH was highly frequent among patients with ADPKD at dialysis initiation, and HtARIH volume was a significant factor for age and htTKV at dialysis initiation. HtARIH was also a significant factor for changes in htTKV, but it was not a significant factor for changes in eGFR for 5 years before dialysis initiation. These results of this study suggest that renal cyst bleeding may accelerate the enlargement of polycystic kidneys. These results also may explain the discrepancy between straight decline of eGFR and accelerating increase of TKV in ADPKD at ESKD.
