Patient and caregiver perspectives on substance use in children and adolescents with chronic kidney disease: a systematic review and thematic synthesis

Certificate Output Instructions

For best output, select "Paper Size" as "A4" and "Margin" as "0" or "None".

To save or print to PDF, please select Print Destination > Save as PDF, enable Background Graphics under "More Settings", then click "Save".

Presented the abstract " "
(Abstract co-author(s): )

Back

E-Poster Presentation

During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.

Preparing your E-Poster

Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.

E-Poster Submission Deadline

Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.

E-Poster Format Requirements

PDF file
Layout: Portrait (vertical orientation)
One page only (Dim A4: 210 x 297mm or PPT)
E-Poster can be prepared in PowerPoint (one (1) PowerPoint slide) but must be saved and submitted as PDF file.
File Size: Maximum file size is 2 Megabytes (2 MB)
No hyperlinks, animated images, animations, and slide transitions
Language: English
Include your abstract number
E-posters can include QR codes, tables and photos

E-Poster

https://storage.unitedwebnetwork.com/files/1099/380aa725086694186a7ee81e60118d79.pdf

Abstract Title *

Patient and caregiver perspectives on substance use in children and adolescents with chronic kidney disease: a systematic review and thematic synthesis

Please follow the instructions below to input your abstract title.

Abstract titles should be brief and reflect the content of the abstract.

The title will not be accepted if it exceeds 25 words.
Type in CAPITAL LETTERS.
Lowercase may be used for abbreviations only, for example, mRNA.

Co-author 1

Anastasia Hughes anastasia.hughes@sydney.edu.au University of Sydney Sydney School of Public Health Sydney Australia *

Co-author 2

Germaine Wong germaine.wong@health.nsw.gov.au University of Sydney Sydney School of Public Health Sydney Australia -

Co-author 3

Allison Jaure allison.jaure@sydney.edu.au University of Sydney Sydney School of Public Health Sydney Australia -

Co-author 4

Co-author 5

Co-author 6

Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

Substance use increases the risk of mortality, morbidity including cardiovascular and pulmonary diseases, progression of CKD, and hospitalisation in patients with CKD. In adolescents and young people with CKD it is estimated that 39% used alcohol, 17% used e-cigarettes use, 16% used cigarettes, and 15% used marijuana. However, Little is known about the perspectives of children with CKD and their caregivers. The aim of this study was to identify the perspectives of children with CKD and their caregivers on substance use.

Methods

We searched MEDLINE, Embase, PsycINFO, and CINAHL from database inception to October 2025 for all studies that reported the perspectives of children with CKD and their caregiver’s perspective on substance use. The content of these studies was thematically analysed.

Results

We identified 17 studies, from which five themes were identified. Uncertain of risks to the kidney highlighted patients and caregivers with limited knowledge on the effects of substance use to their health, graft and tolerance level. Desiring independence and ability to ascertain responsible use encompassed patients highlighting a lack of information on substance use and kidney health and lack of communication between patients and their health professionals. Restrictions impeding on social acceptance and participation involved patients losing a sense of normality and feeling different to their peers. A coping mechanism for pain and stress included using substances as a copy strategy. Guilt and unworthiness involved patients questioning whether they deserve of a transplant due to their substance use behaviours.

Conclusion

Preventing and managing substance use in children with CKD remains clinically challenging along with potential under-diagnosis of substance use due to lack of screening and disclosure by patients. Children with CKD, and caregivers identified the challenges of co-occurring substance use and CKD, whilst highlighting opportunities and strategies to prevent and manage substance use in children with CKD. Further in-depth understanding of the perspectives and experiences of children and caregivers are needed to improve substance use in children with CKD.

Kewords