HEPATORENAL SYNDROME AT NIAMEY NATIONAL HOSPITAL

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HEPATORENAL SYNDROME AT NIAMEY NATIONAL HOSPITAL

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Co-author 1

MOUSSA TONDI ZEINABOU MAIGA zeinab_maiga@yahoo.fr Faculty of Health Sciences, Abdou Moumouni University of Niamey NEPHROLOGY NIAMEY Niger *

Co-author 2

BONKANO BAOUA DJIBRILLA bbdjibrilla@gmail.com Faculty of Health Sciences, Abdou Moumouni University of Niamey NEPHROLOGY NIAMEY Niger -

Co-author 3

FANTA OUSSEINI ousseinifanta0@gmail.com Faculty of Health Sciences, Abdou Moumouni University of Niamey HEPATOGASTROENTEROLOGY NIAMEY Niger -

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Introduction

Cirrhosis is a major public health problem in Niger, with a hospital frequency of 35.79% of chronic liver diseases at the National Hospital of Niamey. It is diagnosed at the stage of decompensation, with the main complications being hemorrhages, ascites, and hepatorenal syndrome. The latter poses a diagnostic and therapeutic problem in our context. It is true that the prognosis has been improved by liver transplantation, with a five-year survival rate of 60 to 67%. In Niger, the management of hepatorenal syndrome remains a major challenge due to the lack of liver transplantation.

Methods

This was a prospective cross-sectional study conducted in the hepatology and gastroenterology departments of Niamey National Hospital and the General Reference Hospital between August 2022 and August 2023.

Results

Twenty-nine patients were included, including 23 men and 6 women with a mean age of 53.58 ± 13.19 years. Clinical symptoms were marked, with deterioration in general condition (100%), vomiting (17.24%), diarrhea (24.13%), hematemesis (10.34%), dysuria (27.58%), burning during urination (3.44%), ascites (96.55%), proteinuria/hematuria positive on urine dipstick, hepatomegaly (44.82%), splenomegaly (6.89%), and CVC (27.58%). All of these patients had abnormal liver and kidney function tests with signs of severe liver failure. The most common medical history was positive hepatitis B (27.58%) and use of traditional medicines (96.55%). Treatment was mainly symptomatic and based primarily on diet (100%), hydroelectrolytic rehydration (100%), diuretics (20.68%), antihypertensive drugs (6.89%), antibiotics (62.06%), laxatives (72.41%), and other medications.

Conclusion

Over a period of one year, our prospective study conducted at the National Hospital in Niamey and the General Reference Hospital enabled us to examine certain aspects of renal failure in patients with cirrhosis.

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