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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
People with kidney failure receiving maintenance hemodialysis (HD) have significantly higher cardiovascular morbidity, symptom burden and cognitive impairment compared to the general population. HD-induced ischemia contributes to myocardial stunning, which decreases vital organ perfusion, worsens cardiovascular outcomes and increases symptom burden. Intradialytic cycling has the potential to mitigate cardiac stunning, but its effects have not been assessed in randomized controlled trials (RCTs). This multicenter RCT evaluated the impact of 12 weeks of intradialytic cycling on HD-induced myocardial stunning in adults receiving maintenance HD.
Using RCT methodology, 1-to-1 parallel design, allocation concealment and assessor blinding we evaluated the effect of thrice weekly supervised intradialytic cycling for 12 weeks’ duration on myocardial stunning in adults (> 18 years old) receiving maintenance HD compared with standard care (no intradialytic exercise) in 6 HD centres in Canada and Australia. The primary outcome was change in mean number of cardiac regional wall motion abnormalities (RWMA) at peak HD stress (last 30 min HD) from baseline to 12 weeks measured by echocardiography using speckle tracking analysis. Secondary outcomes included HD recovery time, cognitive function, symptom burden and physical function.
Independent two-tailed t-test and Poisson generalized linear mixed model will be used to analyze the primary outcome. Multiple linear regression will be performed to determine the role of intradialytic exercise and RWMA severity on absolute change in post-dialysis recovery time, cognitive function, symptoms and physical function.
Trial registration number: NCT04877041
Of 355 individuals approached, 125 participants consented to participate in the study (Adelaide n=10; Winnipeg Site 1 n=31, Site 2 n=16; Calgary n=10; Edmonton n=21; London n=26; and Vancouver n=11). At present 101 participants have completed or remain in the study, with 98 having completed the study protocol and 3 to complete the protocol in early 2026.
Analysis of results will be completed in January 2026, and abstract will be updated with results on Jan 14, 2026.
To be added once analysis complete. We anticipate that this trial will provide critical evidence regarding the benefits of exercise during HD, potentially informing clinical practice and guidelines for hemodialysis care.
