DEEP ENDOMETRIOSIS AND IRREVERSIBLE RENAL IMPAIRMENT

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DEEP ENDOMETRIOSIS AND IRREVERSIBLE RENAL IMPAIRMENT

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Co-author 1

Michael Fanta michael.fanta@volny.cz General University Hospital nad First Faculty of Medicine Dept. of Gynecol., Obstetr. and Neonatology Prague Czech Republic *

Co-author 2

Kvetoslav Novak kvetoslav.novak@vfn.cz General University Hospital nad First Faculty of Medicine Dept. of Urology Prague Czech Republic -

Co-author 3

Zdenka Lisa zdenka.lisa@vfn.cz General University Hospital nad First Faculty of Medicine Dept. of Gynecol., Obstetr. and Neonatology Prague Czech Republic -

Co-author 4

Lucie Fantová lucie.fantova@volny.cz Nefrologie, s.r.o. Dept. Of Nephrology Prague Czech Republic -

Co-author 5

Lucie Hornová hornova@nefrologie-praha.cz Nefrologie, s.r.o. Dept. Of Nephrology Prague Czech Republic -

Co-author 6

Kristýna Hlinecká kristyna.hlinecka@vfn.cz General University Hospital nad First Faculty of Medicine Dept. of Gynecol., Obstetr. and Neonatology Prague Czech Republic -

Co-author 7

Michal Mara michal.mara@vfn.cz General University Hospital nad First Faculty of Medicine Dept. of Gynecol., Obstetr. and Neonatology Prague Czech Republic -

Co-author 8

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Introduction

Deep endometriosis is a severe form of endometriosis that can lead to significant complications, including ureteral stenosis and subsequent kidney loss. It is estimated that deep endometriosis affects the urinary system in approximately 1-2% of all endometriosis cases, with the ureters being involved in about 0.1-0.4% of cases. This involvement can lead to ureteral obstruction, hydronephrosis, and ultimately, loss of kidney function if not diagnosed and treated promptly. This study aims to highlight the ongoing health issue of kidney loss due to late diagnosis and treatment of deep endometriosis.

Methods

We conducted a retrospective analysis of prospective follow-up data from 71 patients who underwent surgery for ureteral stenosis caused by deep endometriosis. The patient cohort primarily consisted of women of fertile age, although 6 patients were older than 45 years. The age range of the patients was from 21 to 52 years. The primary outcome measured was the incidence of nephrectomy due to complete renal function loss.

Results

Out of the 71 patients, 10 (14.1%) required nephrectomy due to irreversible kidney damage. The high rate of nephrectomy underscores the critical need for early diagnosis and intervention in patients with deep endometriosis to prevent severe renal complications.

Conclusion

Kidney loss due to deep endometriosis remains a significant health problem, primarily driven by delayed diagnosis. Despite our efforts to raise awareness and inform not only the medical community, this issue persists. This study emphasizes the importance of early detection and timely surgical intervention to preserve renal function and improve patient outcomes.

Kewords