Predictive value of SMAQ Score in Detecting Non-compliance and Non-adherence in Live-Related Kidney Transplant Recipients.

Certificate Output Instructions

For best output, select "Paper Size" as "A4" and "Margin" as "0" or "None".

To save or print to PDF, please select Print Destination > Save as PDF, enable Background Graphics under "More Settings", then click "Save".

Presented the abstract " "
(Abstract co-author(s): )

Back

E-Poster Presentation

During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.

Preparing your E-Poster

Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.

E-Poster Submission Deadline

Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.

E-Poster Format Requirements

PDF file
Layout: Portrait (vertical orientation)
One page only (Dim A4: 210 x 297mm or PPT)
E-Poster can be prepared in PowerPoint (one (1) PowerPoint slide) but must be saved and submitted as PDF file.
File Size: Maximum file size is 2 Megabytes (2 MB)
No hyperlinks, animated images, animations, and slide transitions
Language: English
Include your abstract number
E-posters can include QR codes, tables and photos

E-Poster

https://storage.unitedwebnetwork.com/files/1099/97bde1e1c3bc0d1c371064583c2ee4db.pdf

Abstract Title *

Predictive value of SMAQ Score in Detecting Non-compliance and Non-adherence in Live-Related Kidney Transplant Recipients.

Please follow the instructions below to input your abstract title.

Abstract titles should be brief and reflect the content of the abstract.

The title will not be accepted if it exceeds 25 words.
Type in CAPITAL LETTERS.
Lowercase may be used for abbreviations only, for example, mRNA.

Co-author 1

Magdy Elsharkawy magdi35@hotmail.com Ain Shams University Internal Medicine, Nephrology & Transplantation Cairo Egypt *

Co-author 2

Salma Fathy safare411@med.asu.edu.eg Ain Shams University Internal Medicine, Nephrology & Transplantation Cairo Egypt -

Co-author 3

Ahmed Abdel Maboud ahmeddoudou1995@gmail.com Ain Shams University Internal Medicine, Nephrology & Transplantation Cairo Egypt -

Co-author 4

Shaimaa Zaki nanajettan@gmail.com Ain Shams University Internal Medicine, Nephrology & Transplantation Cairo Egypt -

Co-author 5

Co-author 6

Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

Non-adherence to immunosuppressive medication is negatively linked to poor clinical outcomes in kidney transplant recipients (KTRs) and the lack of a valid and reliable measurement of adherence represents an obstacle. This study aimed to assess the validation of the Simplified Medication Adherence Questionnaire (SMAQ) in non-adherence/noncompliance in KTRs.

Methods

A Prospective study selected 77 live-related KTRs from 190 KTRs from Ain Shams University Transplant Unit. All patients were subjected to SMAQ and pill count (PC) after analysis; KTRs were divided into: compliant/adherent KTRs (N=23) (PC >95% and SMAQ Score 0), compliant/non-adherent KTRs (N=35) (PC >95% and SMAQ Score >1), non-compliant/non-adherent KTRs (N=19) (PC <95% and SMAQ Score >1). All laboratory work and drug levels were assessed monthly during the study period.

Results

The prevalence of non-adherence was 70.12% (54 KTRs), while the prevalence of low PC within safety margin (95-80% PC) was 23.37% (18 KTRs) and low PC was below 80% was 1.29% (1 KTRs). SMAQ could predict non-compliance/non-adherence for Calcineurin inhibitor (CNI), Mycophenolate mofetil (MMF), and steroids with AUC 0.715, 0.708, and 0.779 respectively and with sensitivity in MMF, and steroids 84.2%, and 89.5% respectively while its specificity and NPV in CNI was 91.4%, and 82.8% respectively. SMAQ score was negatively correlated with PC in CNI, MMF, and steroid p-value <0.001. The causes related to non-adherence were routine and forgetfulness for CNI and steroid while for MMF drug adverse effect was 36.8% (7 KTRs), the number of family members (p-value 0.040), and pregnancy within one-year post-transplant for CNI, MMF, and steroid p-values 0.022, 0.043, and 0.026 respectively. There were no significant differences between groups in the type of rejection, serum creatinine at 3 months, and at 1-year p-value >0.05.

Conclusion

SMAQ could be used as tool for prediction and screening of noncompliance/non-adherence and a longer duration of follow-up is needed for the assessment of the impact of noncompliance/non-adherence on outcomes. Our patients were counseled to avoid noncompliance/non-adherence behavior.

Kewords