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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Low muscle mass and increased visceral fat are associated with increased mortality and adverse health outcomes, but measurement of components of body composition is not routine in clinical practice. Creatinine Muscle Index (CMI), the product of serum creatinine and eGFRcys, has been described as a novel surrogate marker for muscle mass. Waist-hip ratio (WHR) is a recognised surrogate marker for visceral adiposity. We sought to study the associations of CMI and WHR on survival, cardiovascular events and CKD progression.
This was a prospective observational cohort study of 1732 people with CKD category G3 and followed up for 5 years. The primary outcomes were time to cardiovascular events and all-cause mortality over a 5-year period, and secondary outcome was progression of CKD. We included age, sex, serum albumin and Body Mass Index (BMI) in the multivariable Cox model for all-cause mortality at 5 years.
Participants in the higher tertiles of CMI were younger, more likely to be male, less likely to have diabetes, had higher serum albumin, lower BMI and lower waist-to-hip ratio. 248 participants (14.3%) died prior to their year 5 visit. In multivariable Cox proportional hazards model for mortality at 5 years, each one standard deviation decrease in CMI was associated with 34% higher risk in mortality (HR 1.341, 95% CI 1.136-1.583, p<0.001). Cardiovascular events occurred in 605 (34.9%) of participants. Each standard deviation increase in WHR was significantly associated with 16% higher risk of cardiovascular events at 5 years (HR 1.16, CI 1.037-1.298, p =0.009). 306 (24.8%) participants evidenced CKD progression. In a multivariable binary logistic regression analysis, lower CMI was associated with a higher risk of progression of CKD at 5 years (OR 1.271, CI 1.060-1.524, p =0.01).
CMI and WHR were observed to be significant predictors of clinical outcomes in people with CKD. These simple and inexpensive surrogate biomarkers of sarcopenia and visceral adiposity can be easily incorporated into daily practice, to enhance risk stratification in people with CKD and inform therapeutic interventions to improve their clinical outcomes.
