A NUMERICAL STUDY OF HEMODYNAMIC EFFECTS ON ARTERIOVENOUS FISTULA CALCIFICATION

Certificate Output Instructions

For best output, select "Paper Size" as "A4" and "Margin" as "0" or "None".

To save or print to PDF, please select Print Destination > Save as PDF, enable Background Graphics under "More Settings", then click "Save".

Presented the abstract " "
(Abstract co-author(s): )

Back

E-Poster Presentation

During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.

Preparing your E-Poster

Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.

E-Poster Submission Deadline

Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.

E-Poster Format Requirements

PDF file
Layout: Portrait (vertical orientation)
One page only (Dim A4: 210 x 297mm or PPT)
E-Poster can be prepared in PowerPoint (one (1) PowerPoint slide) but must be saved and submitted as PDF file.
File Size: Maximum file size is 2 Megabytes (2 MB)
No hyperlinks, animated images, animations, and slide transitions
Language: English
Include your abstract number
E-posters can include QR codes, tables and photos

E-Poster

Abstract Title *

A NUMERICAL STUDY OF HEMODYNAMIC EFFECTS ON ARTERIOVENOUS FISTULA CALCIFICATION

Please follow the instructions below to input your abstract title.

Abstract titles should be brief and reflect the content of the abstract.

The title will not be accepted if it exceeds 25 words.
Type in CAPITAL LETTERS.
Lowercase may be used for abbreviations only, for example, mRNA.

Co-author 1

Zhe Wang cmu_wz@hotmail.com The Second Hospital of Tianjin Medical University Department of Kidney Disease and Blood Purification Tianjin China *

Co-author 2

Huihui Ning nhh18738280887@163.com Tianjin University Department of Mechanics Tianjin China -

Co-author 3

Lihua Wang wlh201cn@126.com The Second Hospital of Tianjin Medical University Department of Kidney Disease and Blood Purification Tianjin China -

Co-author 4

Yaohong Wang yaohong@tju.edu.cn Tianjin University School of Mathematics and KL-AAGDM Tianjin China -

Co-author 5

Dekui Yuan dkyuan@tju.edu.cn Tianjin University State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin China -

Co-author 6

Hewen Li kisskevin@126.com Department of Radiology Department of Radiology Tianjin China -

Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

Arteriovenous fistula (AVF) calcification is a common complication in hemodialysis patients that leads to AVF dysfunction and decreases the AVF survival, but the mechanisms of AVF calcification, especially the role of hemodynamic changes in AVF calcification have not been fully investigated.

Methods

In this study, a computational fluid dynamics (CFD) model was carried out based on AVF, at the distal anastomosis of the cephalic vein and radial artery, generated from a patient-specific Computed Tomography (CT) angiography and Doppler ultrasound image. Hemodynamic factors were considered to explore the mechanisms responsible for the initiation and progression of AVF calcification. Five stages in one cardiac cycle were chosen to be studied for the velocity field, pressure, time-averaged wall shear stress (TAWSS) and oscillatory shear index (OSI).

Reconstruct of 3D model from CT images

Results

Blood pressure was higher in the arteriovenous anastomosis, and variations of great amplitude of pressure were examined during the cardiac cycle. Blood pressure, transient shear stress, TAWSS, and OSI were higher in the arteriovenous anastomosis and at the bottom of expanded outflow vein, and these sites were highly consistent with the calcified areas shown on CT angiography. On the contrary, no calcification was found in sites where streamline was stable, blood pressure didn’t change dramatically, as well as TAWSS and OSI were lower.

Velocity streamlines at the 5 stages of cardiac cycle. Blood pressure at the 5 stages of cardiac cycle The instantaneous wall shear stress at the 5 stages of cardiac cycle

Conclusion

AVF calcification was correlated with hemodynamic changes, which may contribute to further understand the mechanisms of AVF calcification and providing scientific evidence to inform the optimization of surgical strategies and the development of personalized interventional measures in clinical contexts.

Kewords