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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Cardiovascular (CV) disease represents the leading cause of death among kidney transplant recipients (KTRs) with a functioning graft. Existing evidence indicates male sex as an independent predictor for CV events. To further examine sex difference in CV events, we assessed the excess CV risk, defined as risk relative to individuals with normal kidney function, in female and male KTRs, and compared them with those in populations with non-dialysis chronic kidney disease (CKD) and on maintenance dialysis.
This retrospective cohort study utilized de-identified electronic medical records data from TriNetX US Collaborative Network encompassing 69 health care organizations. Adult participants aged between 18 and 75 years with a functioning graft or normal kidney function during the 5-year follow-up period were included in the primary analysis, while those with non-dialysis CKD or on maintenance dialysis were included in an extended analysis. The primary outcome was major adverse cardiac events (MACE). Multivariable Cox proportional hazards models were used to adjust for a range of risk factors, including age, sociodemographic characteristics, and covariates related to hypertension, diabetes, metabolic syndrome, CV disease, and inflammation.
Of 271,199 included participants, 18,948 were female KRTs, 24,373 were male KRTs, 120,184 were female without CKD, and 107,694 were male without CKD. Female KTRs had a fourfold higher risk for MACE compared with female without CKD (HR 4.38 [4.09-4.54]), whereas male KTRs had threefold higher risk than men without CKD (HR 3.40 [3.26-3.55]). Thus, female sex was associated with greater excess CV risk after kidney transplantation, which persisted across all age groups and rejection status after full adjustment (aHR 2.63 [2.46, 2.82] vs. aHR 2.02 [1.90, 2.15]). Moreover, the sex difference in excess CV risk exaggerated as kidney function declined, with female at a disadvantage (CKD: female aHR 1.84 [1.73, 1.96] vs. male aHR 1.61 [1.53, 1.70]), peaking among participants on maintenance dialysis (female aHR 8.42 [7.89, 8.99] vs. male aHR 5.77 [5.42, 6.14]), while kidney transplantation attenuated this disparity (female aHR 2.63 [2.46, 2.82] vs. male aHR 2.02 [1.90, 2.15]).
Women with impaired kidney function consistently exhibited significantly greater excess CV risk than men; however, kidney transplantation mitigated this sex difference in population with kidney failure.
