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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
The complexity of indications for liver transplantation poses a growing challenge in modern transplantology. The co-occurrence of viral, neoplastic, and autoimmune diseases, as well as lifestyle-related conditions, is increasingly observed. This study aimed to analyze the etiological and demographic characteristics of recipients of orthotopic liver transplants (OLT) and simultaneous liver and kidney transplants (SLKT), taking into account differences in gender, age, and the proportion of multiple etiologies (≥2 diagnoses).
Clinical data from a retrospective database of OLT and SLKT recipients from 2008–2024 were cleaned and classified according to a standardized algorithm that allows for the identification of multiple diagnoses. The analysis included age, gender, pre-transplant creatinine level, and the primary cause of liver disease. Particular attention was paid to patient-induced etiologies: alcoholic liver disease (ALD), metabolic dysfunction-associated steatotic liver disease (MASLD), acetaminophen poisoning and death cap mushroom poisoning.
3,217 OLT and SLKT recipients were included. The mean pre-transplant creatinine level was 1.9 ± 0.7 mg/dL. The most common single etiology was alcoholic liver disease (ALD, 15%), which increased to over 22% when multiple etiology cases were included. The next most common diagnoses included PSC, HCV, HCC, PBC, AIH, and Wilson's disease. Mixed etiologies affected 36.9% of recipients (n=1,189), most commonly HCC with HCV/HBV, or AIH with PSC. Men constituted 62% of all recipients and were more likely to be transplanted at an older age (over 50 years old), while women predominated in younger age groups, primarily with autoimmune diseases (AIH, PBC). Patient-induced etiologies (ALD, MASLD, poisoning) were significantly more common in men and in younger age groups (mean age 47±9 years), while autoimmune or cholestatic diagnoses predominated in women.
Over one-third of liver transplants and SLKT were in multiple etiology patients. Men constituted the majority of recipients, particularly in older groups and with lifestyle-related etiologies (ALD, MASLD, poisoning). Autoimmune diseases predominated in women, diagnosed and considered for transplantation at a younger age. The data indicate the growing importance of multifactorial transplant eligibility and demographic profiling in assessing risk and prognosis after transplantation.
