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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Polycythaemia associated with Nephrotic Syndrome (NS) is rare but repeatedly reported in case reports and small series. Typical histologies reported include minimal change disease (MCD), focal segmental glomerulosclerosis and membranous nephropathy. Mechanisms are heterogeneous and include (1) true secondary Erythropoetin (EPO)-driven erythrocytosis from intrarenal hypoxia (eg. renal ischemia, renal vein thrombosis), (2) unmasking or coexistence of a primary/myeloproliferative cause (polycythaemia vera, PV), and (3) rarer suggestions such as ectopic EPO or EPO-like factor production or altered EPO regulation/sensitivity. Different patients have shown different patterns (some with elevated serum/urine EPO; others with low EPO and JAK2 mutations consistent with PV). Polycythaemia is defined as increase in red cell mass, reflected by haemoglobin (Hb) concentration more than16.5 g/dL in men and 16 g/dL in women or haematocrit more than 49% in men and 48% in women (WHO 2017). Massive protienuria leads to renal interstitial oedema which compress peritubular capillaries. Hypercoagulable state and local hypoxia increases EPO production and increased red cell mass causing secondary polycythaemia in NS.
This is a case report from Nephrology department of Ernakulam Medical Centre, Kochi, Kerala, India. A 22-year-old male, non-smoker, presented with bilateral lower limb edema for the past 10 days and facial puffiness for the past 2 days. He had a history of fever two months prior, without any associated symptoms. There were no known comorbidities or previous significant medical history. Systemic examination was unremarkable. He was subsequently evaluated with laboratory investigations, abdominal imaging, and a percutaneous renal biopsy.
Investigations confirmed diagnosis of Nephrotic syndrome with secondary polycythemia. Steroids was initiated and patient had resolution of polycythemia in parallel with remission of NS.
This case report highlights polycythaemia as an unusual association of NS. NS can be associated with secondary erythrocytosis; most evidence comes from case reports/series. Mechanisms are multiple, most commonly EPO-driven secondary erythrocytosis from intrarenal hypoxia (eg. thrombosis / RVT / micro-ischemia) or, less commonly, coexisting PV. Measurement of serum EPO and JAK2 testing are pivotal first steps. Treat NS and investigate for thrombosis/tumour/PV. Erythrocytosis often improves if the nephrotic syndrome is successfully treated.
