EFFECT OF COLD PACK DURATION ON CANNULATION PAIN IN HEMODIALYSIS PATIENTS

 

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EFFECT OF COLD PACK DURATION ON CANNULATION PAIN IN HEMODIALYSIS PATIENTS

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Therat
Chatsirithitikun
Therat Chatsirithitikun noppadon_koh@hotmail.com King Chulalongkorn Memorial Hospital, Thai Red Cross Society Nursing Department Bangkok Thailand *
Patcharin Injan Patcharin.inj@gmail.com King Chulalongkorn Memorial Hospital, Thai Red Cross Society Nursing Department Bangkok Thailand -
Salin Wattanatorn salin.tob@gmail.com King Chulalongkorn Memorial Hospital, Thai Red Cross Society Nursing Department Bangkok Thailand -
Aschariya Wipattanakitcharoen lingwipat@gmail.com Chulalongkorn University and King Chulalongkorn Memorial Hospital Division of Nephrology, Department of Medicine Bangkok Thailand -
Paweena Susantitaphong pesancerinus@hotmail.com Chulalongkorn University and King Chulalongkorn Memorial Hospital Division of Nephrology, Department of Medicine Bangkok Thailand -
Khajohn Tiranathanagul Khajohn_t@hotmail.com Chulalongkorn University and King Chulalongkorn Memorial Hospital Division of Nephrology, Department of Medicine Bangkok Thailand -
Pisut Katavetin pkatavetin@yahoo.com Chulalongkorn University and King Chulalongkorn Memorial Hospital Division of Nephrology, Department of Medicine Bangkok Thailand -
Kearkiat Praditpornsilpa kearkiat@hotmail.com Chulalongkorn University and King Chulalongkorn Memorial Hospital Division of Nephrology, Department of Medicine Bangkok Thailand -
Kullaya Takkavatakarn koykullaya@hotmail.com Chulalongkorn University and King Chulalongkorn Memorial Hospital Division of Nephrology, Department of Medicine Bangkok Thailand -
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Pain is a frequent and critical problem in daily hemodialysis practice. Local cold application before needle insertion is a simple, non-pharmacological method that may reduce pain through cutaneous analgesia. This study aimed to determine the optimal duration of cold pack application to minimize cannulation pain without increasing complications.

A prospective crossover study was conducted in maintenance hemodialysis patients, each serving as their own control. Six sessions were performed sequentially: control (no intervention), followed by cold pack application for 1, 2, 3, 4, and 5 minutes before cannulation. Pain intensity was assessed using a numerical rating scale (0–10) immediately after the procedure (Figure 1). Statistical comparisons were performed using the Friedman test, with pairwise Wilcoxon signed-rank tests and Bonferroni correction. Local complications (erythema, bruising, prolonged bleeding) were monitored after each session.

A total of 31 patients completed all sessions. The median age was 62 years, with 52% male, and the proportion of AVF to AVG access was 26:5. Median pain scores progressively decreased with longer cold pack duration: control 8 (IQR 7–10), 1 minute 7 (5–8), 2 minutes 6 (5–8), 3 minutes 5 (4–6), 4 minutes 4 (3–5), and 5 minutes 3 (2–3). Pain reduction became statistically significant compared with control beginning at 2 minutes (p < 0.001), with the greatest reduction observed after 4–5 minutes of cooling (Figure 2). Pairwise contrasts confirmed significantly lower pain scores at 3–5 minutes compared with shorter durations. Three patients (10%) withdrew due to mild skin irritation after cooling, and no other local complications were observed.



Pre-cannulation cold pack application for 3–4 minutes significantly reduces cannulation pain without increasing adverse effects. This simple, safe, and low-cost intervention can improve patient comfort during hemodialysis.

Kewords