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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
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E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
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Abstract titles should be brief and reflect the content of the abstract.
Dialyzer reuse remains a common practice in many hemodialysis centers to reduce cost and material waste. Dialyzers are disinfected using peracetic acid–based solutions before reuse. Inadequate rinsing may leave residual hydrogen peroxide, posing potential safety risks—especially in patients undergoing online hemodiafiltration (OL-HDF). The optimal rinse volume required for complete peroxide clearance with increasing reuse numbers has not been clearly defined.
We evaluated reused dialyzers at different reuse numbers to determine the cumulative rinse volume required to achieve a negative residual peroxide test at King Chulalongkorn Memorial Hospital, Thailand. Each dialyzer was disinfected using a peracetic acid–based solution (1,300 ppm) as part of the standard reprocessing procedure. Dialysis treatments were performed using the Fresenius 5008 system in OL-HDF mode. Sequential rinsing with treated water was conducted in increments of 3,500; 4,500; 5,500; 6,500; 7,500; 8,500; 9,500; and 10,000 mL. After each rinse step, residual peroxide was measured using standardized hydrogen peroxide test strips until a negative result was achieved. Segmented regression analysis was performed to identify breakpoints in the relationship between the number of dialyzer reuses and the rinse volume required for complete peroxide clearance.
A total of 52 dialyzers across 143 reuse cycles were examined. The median number of reuses was 10 (min-max: 1-19). The median cumulative rinse volume required to achieve a negative peroxide test was 5,500 mL (IQR 4,500–6,500 mL). Median rinse volume increased with higher reuse numbers: 1–5 reuses: 4,500 mL (IQR 3,500–4,500); 6–10: 5,500 mL (IQR 4,500–6,500); 11–15: 5,500 mL (IQR 4,500–6,500); and 16–20: 6,500 mL (IQR 5,500–7,500). A significant difference (p < 0.05) was observed between groups 1–5 and 6–10, and between groups 11–15 and 16–20 (Figure 1). Segmented regression revealed two breakpoints around six and sixteen reuses, beyond which higher rinse volumes were required for peroxide clearance (Figure 2).
The number of dialyzer reuses significantly affects the rinse volume required for peroxide elimination after peracetic acid disinfection. Higher reuse numbers are associated with greater rinse volume requirements. Adjusting rinse protocols according to reuse frequency—and limiting excessive reuse, particularly in OL-HDF—may enhance patient safety and ensure effective reprocessing.
