PERITONEAL DIALYSIS DISCONTINUATION FROM THE VIEW POINT OF NURSING CARE

 

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PERITONEAL DIALYSIS DISCONTINUATION FROM THE VIEW POINT OF NURSING CARE

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Shuzo
Makino
Shuzo Makino 05a14078@gmail.com Osaka General Medical Center nephrology and hypertension Osaka Japan *
Miyuu Tsuchida 05a14078@gmail.com Osaka General Medical Center nephrology and hypertension Osaka Japan -
Akihito Takashima 05a14078@gmail.com Osaka General Medical Center nephrology and hypertension Osaka Japan -
Hiromitsu Miyakawa 05a14078@gmail.com Osaka General Medical Center nephrology and hypertension Osaka Japan -
Nobuhiro Hashimoto 05a14078@gmail.com Osaka General Medical Center nephrology and hypertension Osaka Japan -
Terumasa Hayashi 05a14078@gmail.com Osaka General Medical Center nephrology and hypertension Osaka Japan -
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Although some risk factors for peritoneal dialysis (PD) discontinuation have been reported, those from the view point of nursing staff have been little investigated to date. So, we intended to investigate the impact of the degree of nursing care requirement and the risk of falling assessed at PD start on subsequent PD discontinuation.

We retrospectively analyzed 124 patients who started PD between January 1, 2010 and December 31, 2024. The degree of nursing care requirement was scored in terms of the need for assistance with transfer, eating, and dressing and each score (0-2) was summed (total score was 0-6).  A higher score indicates a greater level of dependency on assistance. Baseline demographic (age, sex, etiology of end-stage kidney disease, episode of heart failure, and malignancy) and clinical data (BMI, blood pressure, eGFR, albumin, hemoglobin, and potassium) were obtained just before PD initiation. Univariate and multivariate Cox regression model were adopted to determine the risk factors for PD discontinuation.

Median age was 70 and 72% was male. Diabetic nephropathy (DN) accounted for 36% of the etiology of end-stage kidney disease. A total of 94 patients discontinued PD during the observation period of 4543 patient・months. The reasons for discontinuation were death (n=11), transfer to hemodialysis for various reasons (PD associated infection, n=29; volume overload, n=27; solute retention, n=5; and others, n=22). Univariate analysis showed the degree of nursing care requirement (HR, 1.193; 95%CI, 1.011-1.407; P 0.036) and etiology other than DN (HR, 0.590; 95%CI, 0.391-0.891; P 0.012) were significantly associated with PD discontinuation. On multivariate analysis, the degree of nursing care requirement remained significant (HR, 1.228; 95%CI, 1.037-1.453; P 0.017) after the adjustment for age, sex, etiology, BMI, and eGFR.

The result may suggest that intervention from a nursing perspective, especially maintenance of ADLs prior to the introduction of dialysis, is important for long-term continuation of peritoneal dialysis.

Kewords