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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Acute kidney injury (AKI) is a major contributor to the morbidity and mortality burden in the peri-operative period after cardiac surgery and is also associated with increased cardiovascular mortality in the long term. Existing studies have suggested that early and aggressive intervention with continuous veno-venous haemo-filtration (CVVH) reduces mortality in post-operative AKI patients though there is limited data on the long term survival trajectories of these patients. This retrospective study assesses the clinical impact of AKI requiring CVVH on outcomes in cardiac surgical patients at a high-volume quaternary centre.
Data were collected from our institutional registry and from the UK National Mortality Database for all adult cardiac surgeries performed between January 2015 and January 2025. After excluding those requiring pre-operative RRT, all patients whose post-operative recovery was complicated by AKI requiring CVVH were identified. To determine a control group, patients who required CVVH were matched in a 1:2 ratio with patients whose post-operative recovery was not complicated by CVVH requirement. Matching was conducted using the nearest-neighbour method based on a logistic regression model that included the covariates from the EuroSCORE II cardiac surgical risk stratification score. In-hospital outcomes (mortality, post-operative complications and length of hospital stay) and post-discharge outcomes (long-term survival) were compared between groups.
A total of 16,681 patients underwent cardiac surgery during the study period. Of these, 510 patients required post-operative CVVH for AKI; 1020 matched controls were identified. Groups generally had comparable pre-operative and demographic characteristics. In-hospital mortality was significantly higher in patients who received CVVH compared to the control group (23.1% vs 6.2%, p < 0.001). Patients needing CVVH also underwent surgical re-exploration prior to discharge more frequently (18.2% vs 5.3%, p < 0.001). Post-discharge long-term survival was assessed at a median follow up of 39.3 months (IQR 12.9–78.6). Patients who required CVVH during the acute post-operative phase demonstrated significantly higher mortality at all key timepoints and also poorer long-term survival (Figure 1). However, when conditional survival to hospital discharge was applied, long-term survival was comparable between groups (HR 1.23, 95% CI 0.95-1.58, p = 0.115) implying that long-term mortality following AKI in these patients is dependent on acute recovery rather than any delayed complications such as the development of chronic renal insufficiency.
Following cardiac surgery, AKI requiring CVVH is associated with increased mortality, though patients who survive the acute post-operative period demonstrate similar survival trajectories to a matched control cohort. These findings highlight the importance of recognising acute deterioration in renal function post-operatively, as early management of AKI confers longer term clinical benefit.
