INDUSTRY-UNIVERSITY-GOVERNMENT COLLABORATION FOR NON-DIABETIC CKD SCREENING ENHANCEMENT: A MUNICIPAL IMPLEMENTATION FRAMEWORK

 

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https://storage.unitedwebnetwork.com/files/1099/f6729a48c4f6ffb59ba88b7254e45336.pdf
INDUSTRY-UNIVERSITY-GOVERNMENT COLLABORATION FOR NON-DIABETIC CKD SCREENING ENHANCEMENT: A MUNICIPAL IMPLEMENTATION FRAMEWORK

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Takahiro
Imaizumi
Takahiro Imaizumi imaizumi.takahiro.r7@f.mail.nagoya-u.ac.jp Nagoya University Graduate School of Medicine Department of Nephrology Nagoya Japan * Nagoya University Graduate School of Medicine Department of Clinical Research Education Nagoya Japan
Yuko Asano asano.yuuko.m5@s.mail.nagoya-u.ac.jp Nagoya University Graduate School of Medicine Department of Nephrology Nagoya Japan -
Kenta Mitsubayashi mitsubayashi29@med.nagoya-u.ac.jp Nagoya University Graduate School of Medicine Department of Nephrology Nagoya Japan -
Koya Nagase nagase.koya.v2@s.mail.nagoya-u.ac.jp Nagoya University Graduate School of Medicine Department of Nephrology Nagoya Japan -
Tomoyasu Yamaguchi yamaguchi.tomoyasu@prevent.co.jp PREVENT Inc. Business Development Department Nagoya Japan -
Kohei Maeda maeda.kohei@prevent.co.jp PREVENT Inc. Business Development Department Nagoya Japan -
Takahiro Miki miki.takahiro@prevent.co.jp PREVENT Inc. Department of Insight Lab Nagoya Japan -
Yuta Hagiwara hagiwara.yuta@prevent.co.jp PREVENT Inc. Chief Executive Officer Nagoya Japan -
Atsushi Nomura nomuranaika@yahoo.co.jp Nomura Naika Department of Nephrology Ichinomiya Japan -
Shoichi Maruyama maruyama.shoichi.y5@f.mail.nagoya-u.ac.jp Nagoya University Graduate School of Medicine Department of Nephrology Nagoya Japan -
 
 
 
 
 

Japan's diabetic nephropathy prevention initiatives have successfully reduced dialysis initiation, but aging populations now face rising non-diabetic chronic kidney disease (CKD), particularly nephrosclerosis. National health policy has shifted toward non-diabetic CKD prevention, yet municipal implementation remains inconsistent. Current uniform screening approaches achieve only 3% disease awareness and 10% consultation rates among Japanese CKD patients. We established an industry-university-government collaboration to develop and evaluate a comprehensive non-diabetic CKD screening system, creating a scalable municipal implementation model.

We developed a multi-stakeholder framework involving Ichinomiya City, Nagoya University, and PREVENT Inc. to create personalized screening interventions for non-diabetic CKD patients. The study employs a two-phase approach: (1) prototype development using PREVENT's 1-million-person corporate health insurance database to identify healthcare utilization patterns through claims data analysis, and (2) regional implementation using Ichinomiya City's national health insurance and health checkup data. Our approach combines claims-derived healthcare behavior clustering with nudge theory-based individualized notification systems, integrated with face-to-face consultation guidance at community pharmacies and multi-professional care coordination. Target population focuses specifically on non-diabetic CKD patients with poor blood pressure control, enabling precise intervention development for this emerging high-risk population.

The target municipality encompasses approximately 60,000 national health insurance enrollees, with approximately 630 non-diabetic CKD patients showing poor blood pressure control identified among 2024 health screening participants. PREVENT preliminary analysis revealed distinct healthcare utilization patterns among non-diabetic CKD patients, where consultation frequency, care continuity, and comorbidity management behaviors were associated with subsequent CKD diagnosis coding and biochemical testing implementation in the following year. Comprehensive outcome indicators were established, encompassing consultation rates, CKD diagnostic codes, laboratory testing implementation, and chronic kidney disease prevention guidance fees in collaboration with municipal data infrastructure. Implementation framework was successfully established, including community pharmacy networks and multi-professional collaboration systems at regional core hospitals.

This project establishes the foundation for developing an evidence-based personalized screening system targeting non-diabetic CKD patients, addressing Japan’s evolving national policy priorities. The preliminary identification of healthcare utilization patterns provides the ground work for developing precision interventions. Our municipality-university-industry collaboration framework provides a replicable framework for nationwide implementation, directly supporting national CKD prevention policy advancement.

Kewords