CLINICAL OUTCOMES OF PERITONEAL DIALYSIS CATHETERS BY INSERTION METHOD: SURVIVAL, COMPLICATION PROFILE, AND MULTIVARIABLE PREDICTORS

 

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CLINICAL OUTCOMES OF PERITONEAL DIALYSIS CATHETERS BY INSERTION METHOD: SURVIVAL, COMPLICATION PROFILE, AND MULTIVARIABLE PREDICTORS

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Carlos Eduardo
Ortiz Castañeda
Rodrigo Quintero Solis rodrigoquinterosolis@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
Citlally Montserrat Villagómez García montse031095@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
Alejandra Sánchez Hernández saher.allen@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
María Fernanda Saavedra Velez fersaavedravz@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
Miguel Ángel Franco Barrera fraba_95@hotmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
Juan Carlos Anaya Zamora jcaz1907@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
Francisco Robles García franciscoroblesg96@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
Miriam Gabriela Nava Vargas mgnava93@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
Karen Giselle Rosas Reyes karen.rosas8099@alumnos.udg.mx University of Guadalajara Tlajomulco University Center Guadalajara Mexico -
Jose Alfredo Sanchez Mendoza jose.sanchez8094@alumnos.udg.mx University of Guadalajara Tlajomulco University Center Guadalajara Mexico -
Ricardo Jazael Garcia Aguilar ricardo.garcia8111@alumnos.udg.mx University of Guadalajara Tlajomulco University Center Guadalajara Mexico -
Jesus Noe Bailon Conteras noebailoncontreras@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -
Maria Fernanda Garcia Sandoval maria.garcia4313@alumnos.udg.mx University of Guadalajara Tlajomulco University Center Guadalajara Mexico -
Carlos Eduardo Ortiz Castañeda ortizmedico@gmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico *
Hugo Sergio Breien Alcaraz breienh@hotmail.com Institute for Social Security and Services for State Workers (ISSSTE). Nephrology Guadalajara Mexico -

The optimal technique for peritoneal dialysis (PD) catheter insertion—percutaneous versus surgical—remains debated. Surgical placement offers direct visualization and fixation, whereas the percutaneous approach is minimally invasive, ambulatory, and facilitates urgent-start PD. We assessed the association between insertion technique and catheter functional survival, identified predictors of complications and catheter replacement, and compared long-term PD outcomes.

We conducted a retrospective observational study (2011–2025) including 491 incident PD patients. Variables included demographics (age, sex, etiology), technical factors (insertion technique: percutaneous or surgical), and clinical outcomes (complication type/classification, catheter replacement, PD program duration). Statistical analyses comprised Pearson’s χ² and Fisher’s exact test for categorical associations; Kaplan–Meier with Log-Rank for catheter and patient survival; multivariable logistic regression (Enter method) and Cox proportional hazards modeling to identify independent predictors. Significance was set at p<0.05.

Mean age was 57.6 ± 15.2 years; 60.9% were male; diabetic nephropathy predominated (68.6%). Insertion technique was percutaneous in 75.6% and surgical in 21.8%. Mean PD duration was 1,458 ± 921 days. Initial complications occurred in 33.6% (early mechanical 17.3%, early infectious 11.6%). A second catheter was required in 36.9% of patients; a third in 8.6%. No significant associations were observed between insertion technique and complication classification (χ²=12.6, p=0.126), specific complications (χ²=21.6, p=0.25), or need for a second catheter (χ²=3.95, p=0.139). Median catheter survival was 24 days (95% CI, 0–54) for percutaneous and 506 days (95% CI, 0–1021) for surgical placement (Log-Rank p=0.021). Overall PD survival was 2,528 days (95% CI, 2,210–2,845) with no difference by technique (p=0.808). By subtype, early infectious complications (peritonitis/tunnelitis) showed the strongest association with replacement (93%), followed by early mechanical (87%) and late mechanical (100%, small n). In multivariable logistic regression, complication classification was the only independent predictor (OR 0.25; 95% CI, 0.19–0.33; p<0.001; reference: no complications), whereas insertion technique was not significant (OR 0.89; 95% CI, 0.52–1.53; p=0.675). In Cox analysis, the hazard ratio for percutaneous versus surgical technique was 0.97 (95% CI, 0.72–1.31; p=0.83).

Insertion technique did not drive outcomes: percutaneous and surgical approaches yielded equivalent catheter and patient survival. Rather, early infectious and early mechanical complications determined replacement risk, while absence of complications reduced the odds by 75% (OR 0.25; p<0.001). These results shift the focus from how we insert to how we prevent early complications—emphasizing infection control, exit-site care, and proactive mechanical troubleshooting. Given its lower invasiveness and urgent-start feasibility, the percutaneous technique warrants broad adoption, alongside programmatic investment in complication-prevention bundles.

Kewords