HIGH MORTALITY ASSOCIATED WITH KIDNEY DYSFUNCTION IN COVID-19 PATIENTS- INSIGHTS FROM THE TANZANIAN EXPERIENCE

 

Certificate Output Instructions

For best output, select "Paper Size" as "A4" and "Margin" as "0" or "None".

To save or print to PDF, please select Print Destination > Save as PDF, enable Background Graphics under "More Settings", then click "Save".

 


 

Certificate Background

   

Presented the abstract " "
(Abstract co-author(s):  )

 

 

E-Poster Presentation

During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center. 

Preparing your E-Poster

Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.

​E-Poster Submission Deadline

Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.​

E-Poster Format Requirements
  • PDF file
  • Layout: Portrait (vertical orientation)
  • One page only (Dim A4: 210 x 297mm or PPT)
  • E-Poster can be prepared in PowerPoint (one (1) PowerPoint slide) but must be saved and submitted as PDF file.
  • File Size: Maximum file size is 2 Megabytes (2 MB)
  • No hyperlinks, animated images, animations, and slide transitions
  • Language: English
  • Include your abstract number
  • E-posters can include QR codes, tables and photos
https://storage.unitedwebnetwork.com/files/1099/703cf757bc1f3b290ee2e84d1ec17bfb.pdf
HIGH MORTALITY ASSOCIATED WITH KIDNEY DYSFUNCTION IN COVID-19 PATIENTS- INSIGHTS FROM THE TANZANIAN EXPERIENCE

Please follow the instructions below to input your abstract title.

Abstract titles should be brief and reflect the content of the abstract.

  • The title will not be accepted if it exceeds 25 words.
  • Type in CAPITAL LETTERS.
  • Lowercase may be used for abbreviations only, for example, mRNA.
Huda
Al Akrabi
Huda Al Akrabi drakrabi@gmail.com KCMC University Internal Medicine Moshi Tanzania *
Sweetness Laizer s.laizer@kcri.ac.tz KCMC University Clinical Research Moshi Tanzania -
Andrea Constantin myofficialmailtz@gmail.com KCMC Hospital Internal Medicine Moshi Tanzania -
Kajiru Kilonzo kajiru@yahoo.com KCMC University Internal Medicine Moshi Tanzania -
-
-
-
-
-
-
-
-
-
-
-

Kidney dysfunction is a frequent yet underrecognized complication of COVID-19 and a major driver of poor outcomes. Data from sub-Saharan Africa remains limited, despite the region’s vulnerability to resource constraints and delayed diagnosis. We evaluated the burden, predictors, and mortality associated with kidney dysfunction among hospitalized COVID-19 patients in northern Tanzania.

We performed a hospital-based cross-sectional study of adults with RT-PCR–confirmed COVID-19 admitted to Kilimanjaro Christian Medical Centre between March 2020 and January 2022. Demographic, clinical, and laboratory variables were extracted from medical records. Kidney dysfunction was defined as serum creatinine >108 µmol/L (men) or >97.2 µmol/L (women). Logistic regression identified predictors, and Cox proportional-hazards modeling assessed mortality risk.

Among 504 patients (mean age 62.7 ± 17.4 years; 56% male), kidney dysfunction occurred in 215 (42.6%). Independent predictors included age ≥ 60 years (AOR 2.11; 95% CI 1.09–4.07), male sex (AOR 1.56; 95% CI 1.07–2.67), and hypertension (AOR 1.51; 95% CI 1.02–2.24). Mortality among those with kidney dysfunction reached 54%, escalating to 74% during the fourth COVID-19 wave. Advanced age remained a strong predictor of death (AHR 2.32; 95% CI 1.16–4.64).

Kidney dysfunction was highly prevalent and strongly associated with mortality among hospitalized COVID-19 patients in Tanzania. Older age, male sex, and hypertension independently predicted kidney involvement and poor outcomes. Mortality more than doubled in patients with kidney dysfunction and peaked during later pandemic waves, highlighting the combined effects of patient vulnerability and health system constraints. Routine kidney function monitoring, early correction of reversible factors, and strengthened nephrology preparedness should be integral to pandemic response strategies in resource-limited settings, transforming lessons from COVID-19 into readiness for future global health crises.

Kewords