EPIDEMIOLOGY OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE IN THE NORTH RIYADH AREA

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Abstract Title *

EPIDEMIOLOGY OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE IN THE NORTH RIYADH AREA

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Co-author 1

Ali Altayyar dr_ali20007@yahoo.com Riyadh Second Health Cluster Medicine/ Nephrology Riyadh Saudi Arabia *

Co-author 2

Khalid Almatham kalmatham@gmail.com Riyadh Second Health Cluster Medicine/ Nephrology Riyadh Saudi Arabia -

Co-author 3

Amr Harraz amrharraz642@yahoo.com Riyadh Second Health Cluster Medicine/ Nephrology Riyadh Saudi Arabia -

Co-author 4

Amer Yosri ameryousri1982@gmail.com Riyadh Second Health Cluster Medicine/ Nephrology Riyadh Saudi Arabia -

Co-author 5

Hussein Taha husseintaha1974@hotmail.com Riyadh Second Health Cluster Medicine/ Nephrology Riyadh Saudi Arabia -

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Introduction

Autosomal Dominant Polycystic Kidney Disease is defined as a multisystem and progressive disease with bilateral renal cysts formation accompanied by kidney enlargement and other organ involvement, such as the heart, liver, pancreas, spleen, and arachnoid membranes.

International prevalence is around 1 cases in 1000 population. It is very well observed by physicians the high number of patients that we see in clinical practices compared to international prevalence.

Methods

It was a cross sectional study that is open for general population to do Ultrasound screening for diagnosis of Autosomal Dominant Polycystic Kidney Disease. Followed by detailed investigations in positive patients that include dictated Ultrasound imaging, clinical examination, and blood tests related to the disease.

Results

The general prevalence was 33 cases out of 420 cases screened at community level which equals to 7.5% prevalence among screened group and 75 cases every 1000 cases. Majority of the positive patients were among age group from 30-59. Most patients were in group 1-2 Chronic kidney disease as this study was done on general population. Obesity were noticed as 40 % of positive patients were obese. Vitamin D low level were observed in 63% of positive patients.

Conclusion

Autosomal Dominant Polycystic Kidney Disease is highly prevalent among population of north Riyadh region. Screening Programs are highly needed over the community level to discover more cases and to establish medical management.

Kewords