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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Background :Chronic kidney disease (CKD) is a growing global health challenge projected to become the fifth leading cause of death by 2040. The burden is greatest in low- and middle-income countries, where diagnostic and treatment capacity are limited. Quantifying the magnitude and determinants of rapid CKD progression in such settings is essential for early intervention and policy action.
Methods: We conducted a retrospective cohort study among adults (≥18 years) with CKD stages 3–5 attending the KCMC renal clinic between January 2019 and May 2024. Clinical, laboratory, and treatment data were extracted from the hospital electronic system. Rapid CKD progression was defined as an annual eGFR decline > 5 mL/min/1.73 m². Multivariable logistic regression identified independent predictors
Results: Of 320 eligible patients, 173 (54.1%) experienced rapid kidney function decline. Among these, hyponatremia was present in 60.7%, hypoalbuminemia in 77.4%, and uncontrolled systolic blood pressure in 85.8%. After multivariable adjustment, low serum albumin (AOR 18.7; 95% CI 3.03–114.98; p < 0.01), hyponatremia (AOR 3.0; 95% CI 1.19–7.38; p = 0.02), and elevated systolic blood pressure (AOR 50.0, p = 0.01) remained independent predictors of RKFD. .
Over half of Tanzanian CKD stage 3–4 patients experienced rapid loss of kidney function, primarily driven by modifiable factors. Early correction of hyponatremia, nutritional optimization to improve serum albumin, and strict control of systolic blood pressure (AOR 50.0; p < 0.01) could substantially delay progression to ESRD. These findings provide a practical framework for risk-based CKD management in low-resource settings and support integration of nutrition and electrolyte monitoring within national NCD programs. This first Tanzanian study quantifying modifiable drivers of RKFD using eHMS-linked data offers actionable insights for prevention, registry design, and targeted clinical follow-up at KCMC.
