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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Uraemic pruritus (UP) is a frequent and distressing complication in dialysis patients, but its mechanisms remain poorly understood. Beyond biochemical and neurological factors, the role of skin chromaticity—reflecting melanin and hemoglobin content—has rarely been examined. This study investigated the association between skin color parameters and both the occurrence and severity of post-dialysis pruritus in chronic kidney disease (CKD) patients.
A total of 256 dialysis patients from a single center were enrolled. Pruritus severity was assessed using the UP-Dial scale and classified as no (n = 90), mild (n = 120), moderate (n = 26), or severe (n = 20). Skin color at healthy sites was measured with a colorimeter to obtain CIE-Lab* values, and the Individual Typology Angle (ITA°) was used for skin type classification. Associations between color parameters and pruritus outcomes were analyzed.
Significant differences were observed in the distribution of pruritus occurrence among skin color groups defined by ITA° (p = 0.0013), with patients in the “Very Light” skin type showing a relatively higher proportion of those without pruritus. Multivariate linear regression further identified skin lightness (L*) and Individual Typology Angle (ITA°) as negative predictors of pruritus occurrence (β = –0.153, p < 0.001; β = –0.052, p < 0.001, respectively), whereas yellowness (b*) was a positive predictor (β = 0.153, p = 0.013).
In terms of severity, across skin tone categories, lighter skin groups (Very Light, Light) showed a predominance of mild pruritus (>70%), while intermediate tones exhibited a more balanced distribution between mild and moderate-to-severe cases. Darker skin types (Tan, Brown) displayed a slightly higher proportion of severe pruritus. However, no significant differences were found in pruritus severity distribution across ITA° groups (p = 0.248). Likewise, multivariate regression indicated no significant associations between pruritus severity and skin color parameters (L*: p = 0.315; a*: p = 0.152; b*: p = 0.436; ITA°: p = 0.348).
This single-center study suggests that skin chromaticity may influence the likelihood of developing post-dialysis pruritus, though it does not appear to affect its severity. These findings highlight skin color as a potential individual-level factor contributing to susceptibility to uraemic pruritus, warranting validation in larger, multi-center studies.
