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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Poor sleep quality, fatique, and cognitive dysfunction are frequent complaints reported by hemodialysis patients, caused by a combination of factors including uremic toxins, sleep disorders, stress, and the dialysis process itself. This study aims to investigate the prevalence of poor sleep, fatique, and its relationship with cognitive dysfunction in regular hemodialysis patient.
All adult patients age ≥18 years who routinely underwent hemodialysis sessions twice a week for ten cumulative hours for at least twelve consecutive weeks, at a tertiary hospital in North Sumatera, Indonesia, were screened for symptoms. We excluded patients with acute illness. Data were collected using a self-reported questionnaire. We used the Indonesian version of the Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality, the Indonesian version of the Functional Assessment Chronic Illnes Therapy (FACIT-F) to identify fatique level and the Indonesian version of the Mini-Mental State Examination (MMSE) for cognitive dysfunction screening. Univariate and multiple regression analyses were used to determine significant factors associated with cognitive dysfunction. Statistical significance was set at p≤0.05.
In this cross-sectional design, included 151 patients (55.0% male) and 58% of the participants had been on HD for <3 years. Seventy one percent were unemployed and 77.5% had no more than a high-school education. The comorbid conditions were hypertension (69.0%) and diabetes (42.0%). The mean global PSQI score was 6.42±5.17, with 77.0% of participants scoring >5, indicating poor sleep. Increased age was associated with poorer sleep (p<0.001). Almost all of patients (91.0%) experienced moderate to high level of fatique. Older patients and poorer sleep had significantly higher fatigue levels (p<0.001, respectively).The mean global MMSE score was 7.26±4.38, with 45.0% of participants experienced severe cognitive dysfunction. Regression analysis showed that older patients (4.94, 95%CI;1.87-14.07), poorer sleep (1.47, 95%CI;1.54-12.78) and fatique (5.24, 95%CI;1.72-16.00) significantly affected sleep quality cognitive dysfunction (p=0.001, p=0.024 and p=0.004, respectively).
This is the first study to examine sleep quality, fatigue, and cognitive dysfunction in HD patients. This study highlights the high prevalence of these symptoms and underscores their interrelationship. Our findings will enable dialysis clinicians to explore the underlying causes associated with increased risk of cognitive dysfunction in HD patients, and to develop appropriate management strategies.
Future research may benefit from focusing on a longitudinal study design and interventional trials that target self-management of poor sleep and fatigue symptoms could potentially reduce the total burden of symptoms in enhancing cognitive dysfunction in HD patients.
