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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
The first kidney transplant in Syria was conducted in 1979 at Harasta Hospital in Damascus. The donor was a living relative, and the recipient was administered basic immunosuppressive therapy. Despite this, the renal allograft functioned effectively for more than 25 years. The success of kidney transplants is heavily influenced by the compatibility of Human Leukocyte Antigen (HLA) types between donors and recipients. This is further evidenced by the remarkably low occurrence of chronic allograft nephropathy in transplants from HLA-identical, living-related donors, underlining the crucial role of immunological factors. Since the introduction of this medical technology, an ongoing debate has revolved around the significance of HLA matching in kidney allograft survival. While recent studies have suggested a diminishing role of HLA compatibility, counterarguments emphasize its continued importance. To address these discrepancies, this study aims to examine the impact of HLA compatibility on kidney allograft survival by analyzing transplants from live donors conducted at a single center in Syria. The objective of this research was to prospectively investigate the relationship between post-transplant HLA class I and/or class II panel reactive antibodies and the success or failure of grafts.
The records from the kidney transplant center were analyzed, encompassing the HLA genotype data of patients who had undergone a kidney transplant. We studied 84 first kidney recipients transplanted at a single center, with a graft functioning for at least 1 years. The HLA genotype was assessed in relation to transplant success, taking into account factors such as creatinine clearance and graft survival during the perioperative phase and subsequent follow-up evaluations. Genotypes showing the strongest correlation with favorable transplant outcomes were identified, aiming to enhance predictions of kidney transplant success through pre-transplant genetic analysis, while accounting for other influencing factors.
The most common HLA types associated with high transplant success rates include:
HLA-A Alleles: The most frequent alleles identified in the Syrian kidney transplant patents are A01, A02, A03, A11 and A24. These alleles have been shown to correlate with better transplant outcomes due to their higher compatibility rates.
HLA-B Alleles: Common alleles include B35, B41, B44 and B51. These alleles are also critical in determining compatibility and have been associated with improved graft survival.
HLA-DR Alleles: compatibility in this class is equally important for reducing the risk of rejection. we found that Common alleles include DR03, DR04, DR07 and DR11. and It is clear that it may have an important role in graft survival and kidney transplant success.
To conclude, our findings suggest that certain histological patterns within the Hala system could influence the long-term success of kidney transplantation. This insight may prove valuable in patient preparation and in correlating genetic data with donor histological characteristics. Additionally, it highlights the importance of managing other pathological and immunological factors affecting kidney graft survival and transplant outcomes in Syrian patients.
