Epidemiological Analysis of Acute Kidney Injury Treatment in the Brazilian Public Health System (SUS)

 

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https://storage.unitedwebnetwork.com/files/1099/e2c07bcfa1df9b3eb908f8123c657cf4.pdf
Epidemiological Analysis of Acute Kidney Injury Treatment in the Brazilian Public Health System (SUS)

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Geraldo
Bezerra da Silva Júnior
Davi Pierre daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Dina Magalhães daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Rafael Odon daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Samira Belisário daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Luana Osterno daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Beatriz Pinho daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
André Libório daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Isabela Diógenes daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Amanda Costa daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Janilson Felix daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Camilla Graça daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
João Davi De Assis daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Maria Sofia Bezerra daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Brazil -
Ryan Coutinho daavipierre@gmail.com University of Fortaleza Medicine Fortaleza Bermuda -
Geraldo Bezerra da Silva Júnior geraldobsilvajr@yahoo.com University of Fortaleza Medicine Fortaleza Brazil *

Acute Kidney Injury (AKI) is a serious global health problem, associated with high morbidity, mortality, and hospital costs. In Brazil, its burden on the Unified Health System (SUS) is intensified by population aging and the growing prevalence of chronic diseases, demanding frequent hospitalizations and advanced care. Analyzing AKI-related admissions, outcomes, and expenditures is crucial to support health policies, optimize resource allocation, and improve patient management.

An analysis of the Brazilian Unified Health System (SUS) was done, in order to investigate how AKI treatment is in Brazil, from 2010 to 2025. All publicly available data were included and a statistical analysis was done using SPSS, v.20.0.

Between July 2010 and July 2025, a total of 73,938 hospital admissions for the treatment of AKI were recorded in Brazil. The total number of deaths was 13,469, resulting in an overall mortality rate of 18.2%. The mean length of hospital stay was 12.6 days, totaling 929,915 hospital days during the study period. The total cost of these hospitalizations was US$ 175,840,928.80, with a mean cost per admission of US$ 2,378.22. Both total expenditure and mean cost per patient showed a progressive increase over the historical series, peaking in years with the highest number of admissions. Temporal analysis revealed an absolute increase in the number of hospitalizations and deaths throughout the study period, although the mortality rate remained relatively stable, with annual variations of less than 2 percentage points. The peak of admissions and expenditures was observed in the post-pandemic period, possibly reflecting health system overload. Regionally, the Southeast concentrated the highest absolute number of admissions and costs, while the Northeast showed proportionally higher mortality despite a shorter mean hospital stay. Statistically significant differences were identified among regions for all analyzed indicators (p < 0.05).

The findings from DataSUS demonstrate that AKI is not only a disease of high morbidity and mortality (18.2%) but also incurs increasing hospital costs. Between 2010 and 2025, there were 73,938 hospitalizations nationwide, with an average length of stay of 12.6 days and an average cost of US$ 2,378.22 per hospitalization. These data reveal an absolute increase in hospitalizations and deaths, with significant regional disparities, highlighting the need for prevention policies, efficient management, and appropriate allocation of resources.

Kewords