NAVIGATING MOTHERHOOD WITH END-STAGE RENAL DISEASE: A CASE OF SUCCESSFUL PREGNANCY ON HEMODIALYSIS

 

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NAVIGATING MOTHERHOOD WITH END-STAGE RENAL DISEASE: A CASE OF SUCCESSFUL PREGNANCY ON HEMODIALYSIS

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Hafiza
Farzana
Hafiza Farzana hafizafarzana2007@gmail.com Dhaka Medical College Hospital Feto Maternal Medicine Dhaka Bangladesh *
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Pregnancy in women with end-stage renal disease (ESRD) is exceptionally rare due to impaired fertility, anovulation, and hormonal imbalance. When it occurs, it is associated with increased maternal and fetal risks including pre-eclampsia, fluid overload, uremia, and poor placental perfusion, often leading to miscarriage, fetal growth restriction (FGR), or preterm birth. Recent advancements in renal replacement therapy, nutrition, and multidisciplinary perinatal care have improved pregnancy outcomes in this population. This report presents a rare case of successful pregnancy outcome in a woman with ESRD managed with intensive hemodialysis and other supportive managements.

A 28-year-old woman, incidentally diagnosed with pregnancy at 4 months’ gestation, was found to have serum creatinine 11 mg/dL and hemoglobin 6 g/dL, confirming ESRD. She was counseled regarding high maternal and fetal risks and advice to terminate pregnancy but she opted to continue the pregnancy. The patient was referred to a tertiary care center where a multidisciplinary team involving nephrology, obstetrics, nutrition, and neonatology provided coordinated management. Daily hemodialysis (six sessions per week) was initiated to maintain pre-dialysis blood urea below 50 mg/dL. Blood pressure, electrolytes, hemoglobin, and nutritional status were closely monitored. Erythropoietin, iron supplementation, and antihypertensive therapy were administered as required. Serial ultrasonography and Doppler assessments were performed to monitor fetal growth and well-being.

Despite optimal management, fetal growth restriction developed in the third trimester. At 34 weeks’ gestation, spontaneous preterm labor occurred. Hemodialysis was performed prior to delivery to stabilize maternal biochemical status. The patient delivered vaginally a live female infant weighing 1500 grams. Postpartum dialysis was continued to maintain metabolic balance. Both mother and baby had an uneventful recovery with no major complications.

This case highlights that successful pregnancy is achievable in women with ESRD through intensive hemodialysis, strict metabolic control, and multidisciplinary collaboration. Early referral to specialized centers, individualized management, and patient motivation are essential for optimizing outcomes. With commitment and coordinated care, even pregnancies complicated by ESRD can conclude in favorable maternal and neonatal results.

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