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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Leptospirosis, which is caused by Leptospira, is a prevalent zoonotic disease worldwide. However, it remains underreported in Taiwan due to its nonspecific clinical manifestations and limited awareness among healthcare providers. While most cases are mild or asymptomatic, severe icteric leptospirosis (Weil’s diseases) can lead to multi-organ failure and even death. In Taiwan, the standard diagnostic methods—microscopic agglutination test (MAT) and cultures of blood or urine—are time-consuming and require specialized facilities, often delaying definitive diagnosis.
This retrospective observational study reviewed the medical records of hospitalized patient at Chang Gung Memorial Hospital, a tertiary medical center in Taiwan, from October 1, 2015 to September 30, 2024. Patients diagnosed with severe icteric leptospirosis requiring ICU care were confirmed by positive culture result or MAT. Meanwhile, a rapid IgM screening test was additionally used for early detection. Clinical presentations, organ involvement, treatment, and outcomes were analyzed.
Over the 10-year period, four confirmed cases were identified. Two patients presented with fever and all developed jaundice and acute kidney failure. Three patients required renal replacement therapy, among whom two received continuous renal replacement therapy due to hemodynamic instability requiring inotropic support. Two patients developed respiratory failure necessitating mechanical ventilation. All patients received an IgM serology assay within 3 days of admission and appropriate antibiotic therapy with ceftriaxone, after which their renal function improved and they were successfully extubated. All patients were transferred to general ward and survived their initial hospitalization.
Severe leptospirosis remains an important cause of multi-organ dysfunction, including acute kidney injury, jaundice, and respiratory failure. Early recognition of its characteristic clinical features and timely initiation of appropriate antibiotic therapy are critical for improving patient outcomes. The rapid IgM serology assay serves as a useful screening tool for early detection due to its simplicity and quick turnaround time.
