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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Chronic kidney disease (CKD) is a risk factor for deep vein thrombosis (DVT). However, in contrast, thrombus in the ascending aorta is a rare event due to the rapid blood flow.
A 70-year-old male with a history of heavy alcohol use and CKD (serum creatinine 5.0 mg/dL) was admitted to our hospital with right leg pain and swelling. He had a previous history of DVT, but had discontinued warfarin therapy 2 months prior due to excessive prolongation of prothrombin time-international normalized ratio (PT-INR). Laboratory tests revealed an elevated D-dimer level of 21 µg/mL. Ultrasonography and contrast-enhanced computed tomography (CT) revealed a massive DVT in the right lower extremity, which had not been present 2 months earlier. Additionally, the CT scan showed a massive pulmonary embolism and a 2-cm mass adherent to the wall of the ascending aorta.
To prevent an embolic stroke, surgical removal of the mass was performed. Histopathological examination revealed that the mass was not a tumor, but a thrombus composed of red blood cells, neutrophils, and fibrin. Therefore, warfarin therapy was restarted.
Screening for thrombophilia revealed normal levels of antithrombin activity, protein C and S activity, lupus anticoagulant, and antiphospholipid antibodies. However, hyperhomocysteinemia was detected (188.4 nmol/mL; normal range: 7.0–17.8), along with hypocobalaminemia and folate deficiency. The multivitamin prescription including folate, therefore, was started, and he has been followed regularly.
Cobalamine and folic acid are essential cofactors in homocysteine metabolism, and their deficiency can lead to hyperhomocysteinemia, one reason of thrombopilia.
In this case, the patient’s excessive alcohol consumption and unbalanced diet likely contributed to the development of hyperhomocysteinemia due to vitamin deficiencies, potentially leading to thrombus formation in multiple vascular regions. Moreover, even with apparent reason of thrombophilia, thrombus in ascending aorta is extremely rare.
