THE PREVALENCE, RISK FACTORS, AND IMPLICATIONS OF COMPLICATIONS RELATED TO DIALYSIS CATHETER INSERTION AT A TERTIARY CENTRE IN MALAYSIA

 

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THE PREVALENCE, RISK FACTORS, AND IMPLICATIONS OF COMPLICATIONS RELATED TO DIALYSIS CATHETER INSERTION AT A TERTIARY CENTRE IN MALAYSIA

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Zulkifli
Haninah
Zulkifli Haninah haninahz@gmail.com Hospital Canselor Tuanku Muhriz Department of Medicine Kuala Lumpur Malaysia *
Lim Kuan Yee limkuanyee@gmail.com Hospital Canselor Tuanku Muhriz Nephrology Unit Kuala Lumpur Malaysia -
Mustafar Ruslinda ruslinda.m@gmail.com Hospital Canselor Tuanku Muhriz Nephrology Unit Kuala Lumpur Malaysia -
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Hemodialysis (HD) is a critical treatment for patients with acute kidney injury (AKI) or end-stage renal disease (ESRD). While arteriovenous fistulas (AVFs) and grafts are considered the preferred forms of long-term vascular access, central venous catheters (CVCs) are often necessary in urgent situations or when permanent access is not feasible. This study aimed to determine the prevalence of complications related to hemodialysis catheter insertion at a Malaysian tertiary centre, identify the associated risk factors, and assess their clinical implications, particularly hospital stay duration and mortality.

This was a single-centre, retrospective study conducted at Hospital Canselor Tuanku Muhriz (HCTM) involving all patients who underwent hemodialysis catheter insertion from 1st January 2021 until 31st August 2023. Patients were selected based on specific inclusion and exclusion criteria. Baseline data, including demographics, comorbidities (diabetes mellitus, peripheral vascular disease), and previous catheter-related complications, were reviewed. Medications (antiplatelets, anticoagulants) and laboratory results (platelet count, renal profile, liver function, coagulation profile) were also recorded. The study further examined procedure details, including the operator, insertion site, number of puncture attempts, and complications related to the procedure. Risk factors for complications were analysed.

A total of 824 patients underwent dialysis catheter insertion during the study period. The median age was 62 years, with 56.9% male and 64.4% Malay. The most common comorbidities were hypertension (84.7%), diabetes mellitus (67.6%), and dyslipidemia (79.2%). Over half of the patients had a history of previous catheter insertion (64.1%), and 50.8% had experienced prior catheter-related complications. Most insertions were performed by medical officers (74.3%), and the right internal jugular vein was the most common insertion site (36.8%). A total of 33.9% developed complications, with the most frequent being failed puncture (9.5%), catheter dysfunction (8.3%), and infection (7.4%). Independent predictors of complications included previous catheter insertion (OR 2.30, p<0.001) and multiple puncture attempts (OR 0.19, p<0.001) 

Approximately one-third (33.9%) of patients experienced procedure-related complications, with failed punture, catheter dysfunction and infection being the most common. Complications were linked to prolonged hospital stays but did not significantly affect overall in-hospital mortality. Failed punctures were particularly associated with higher hospitalization rates and extended stays. This study highlights the importance of careful catheter management to minimize complications and improve patient outcomes.

Kewords