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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Renal biopsy is the gold standard for diagnosing anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis in patients presenting with renal dysfunction, obvious hematuria or proteinuria. However, it remains largely unknown whether pathological features can be detected in renal biopsy specimens from patients presenting with preserved renal function and mild proteinuria.
Adult patients diagnosed with ANCA-associated glomerulonephritis based on renal biopsy findings between 2019 and 2025 were analyzed, and patients who had preserved renal function (＞60 ml/min/1.73m2) and mild proteinuria (<1 g/gCr) were included. Patient characteristics, pathological findings and treatment responses were analyzed.
Among 47 patients diagnosed with ANCA-associated glomerulonephritis, 11 were eligible (4 women; median age, 73 years; median eGFR, 71.1 ml/min/1.73m2; median proteinuria, 0.35 g/gCr). Fever was the most common symptom (54.5%), followed by cough (36.4%), extremity pain (27.3%) and other symptoms. All patients presented with at least one symptom and microscopic hematuria. Median serum C-reactive protein was 6.9 mg/dL. Pathologically, tuft necrosis and necrotizing arteritis were observed in 72.7% and 27.3% of patients, respectively. Cellular crescents were present in 90.9% of cases, fibrocellular crescents in18.2%, and fibrous crescents were absent. Overall, acute lesions were detected in all cases. Among the 10 patients with available follow-up, immunosuppressive therapy was initiated in 9 patients. One month after treatment, renal function was preserved, with a median eGFR of 71.1 mL/min/1.73m², and proteinuria decreased to a median of 0.17 g/gCr. Microhematuria resolved in 4 patients.
Renal biopsy should be actively considered, as characteristic histopathological features can often be identified even in patients with ANCA-associated glomerulonephritis who have preserved renal function and mild proteinuria.
